# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5249973 | B | Inhibition of HSP90 in rabbit reticulocyte lysates at 10 uM incubated for 3 hrs by denatured luciferase refolding assay | Oryctolagus cuniculus | 42 | ALA5247613 | subcellular format | Scientific Literature | |
2. | ALA5249975 | B | Inhibition of HSP90 in rabbit reticulocyte lysates incubated for 3 hrs by denatured luciferase refolding assay | Oryctolagus cuniculus | 14 | ALA5247613 | subcellular format | Scientific Literature | |
3. | ALA5249976 | F | Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA5247613 | cell-based format | Scientific Literature | |
4. | ALA5249977 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA5247613 | cell-based format | Scientific Literature | |
5. | ALA5249978 | F | Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA5247613 | cell-based format | Scientific Literature | |
6. | ALA5249979 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA5247613 | cell-based format | Scientific Literature | |
7. | ALA5249980 | F | Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA5247613 | cell-based format | Scientific Literature | |
8. | ALA5250001 | B | Inhibition of HSP90 in human HL-60 cells assessed as increase in HSP27 protein expression incubated for 24 hrs by western blot analysis | Homo sapiens | 2 | ALA5247613 | cell-based format | Scientific Literature | |
9. | ALA5250002 | B | Inhibition of HSP90 in human HL-60 cells assessed as decrease in CDK4 protein expression incubated for 24 hrs by western blot analysis | Homo sapiens | 2 | ALA5247613 | cell-based format | Scientific Literature | |
10. | ALA5250004 | B | Binding affinity to full length HSP90 (unknown origin) expressed in Escherichia coli BL21(DE3) cells at 20 uM by NMR STD assay | Homo sapiens | 1 | ALA5247613 | cell-based format | Scientific Literature |