Inhibition of human Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis
Inhibition of mouse Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis
Inhibition of human Nav1.1/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis
Inhibition of human Nav1.5/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis
Analgesic activity against PSL-induced neuropathic pain mouse model assessed as reversal of thermal hyperalgesia at 1 mg/kg, po measured after 30 mins by plantar test
Analgesic activity against PSL-induced neuropathic pain mouse model assessed as reversal of thermal hyperalgesia at 1 mg/kg, po measured after 60 mins by plantar test
Analgesic activity against PSL-induced neuropathic pain mouse model assessed as reversal of thermal hyperalgesia at 1 mg/kg, po measured after 120 mins by plantar test