| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249295 | Functional | Reversal of P-gp-mediated multidrug resistance in human NCI-ADR-RES cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 10 uM incubated for 48 hrs by MTT assay | Homo sapiens | 23 | ALA5247598 | cell-based format | Scientific Literature | |
| 2. | ALA5249300 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 24 | ALA5247598 | cell-based format | Scientific Literature | |
| 3. | ALA5249301 | Functional | Antiproliferative activity against human multidrug resistant NCI-ADR-RES cells overexpressing P-gp assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 24 | ALA5247598 | cell-based format | Scientific Literature | |
| 4. | ALA5249302 | Toxicity | Cytotoxicity against human HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 23 | ALA5247598 | cell-based format | Scientific Literature | |
| 5. | ALA5249303 | Functional | Reversal fold, ratio of doxorubicin IC50 to doxorubicin IC50 in presence of 10 uM test compound for reversal of P-gp-mediated multidrug resistance in human NCI-ADR-RES cells incubated for 48 hrs by MTT assay | Homo sapiens | 20 | ALA5247598 | cell-based format | Scientific Literature |
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