# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5230267 | Binding | Inhibition of HDAC1 (unknown origin) using Fluor de lys as substrate by fluorescence based analysis | Homo sapiens | 13 | ALA5230083 | single protein format | Scientific Literature | |
2. | ALA5230268 | Binding | Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysis | Homo sapiens | 16 | ALA5230083 | single protein format | Scientific Literature | |
3. | ALA5230269 | Binding | Inhibition of HDAC8 (unknown origin) using Fluor de lys as substrate by fluorescence based analysis | Homo sapiens | 13 | ALA5230083 | single protein format | Scientific Literature | |
4. | ALA5230270 | Binding | Selectivity index, ratio of IC50 for inhibition of HDAC1 (unknown origin) to IC50 for inhibition of HDAC6 (unknown origin) | Homo sapiens | 12 | ALA5230083 | assay format | Scientific Literature | |
5. | ALA5230271 | Binding | Selectivity index, ratio of IC50 for inhibition of HDAC8 (unknown origin) to IC50 for inhibition of HDAC6 (unknown origin) | Homo sapiens | 12 | ALA5230083 | assay format | Scientific Literature | |
6. | ALA5230352 | Functional | Antiproliferative activity against human RPMI-8226 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay | Homo sapiens | 7 | ALA5230083 | cell-based format | Scientific Literature | |
7. | ALA5230353 | Functional | Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay | Homo sapiens | 7 | ALA5230083 | cell-based format | Scientific Literature | |
8. | ALA5230354 | Toxicity | Cytotoxicity against human HS5 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay | Homo sapiens | 5 | ALA5230083 | cell-based format | Scientific Literature | |
9. | ALA5230359 | ADME | Microsomal stability in human liver microsomes assessed as half life at 0.5 uM prewarmed for 5 mins followed by NADPH addition and measured for 90 mins by LC-MS/MS analysis | Homo sapiens | 3 | ALA5230083 | microsome format | Scientific Literature |