# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5251363 | B | Inhibition of recombinant human CDK5/p25 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
2. | ALA5251364 | B | Inhibition of recombinant human CK1epsilon expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
3. | ALA5251365 | B | Inhibition of recombinant human CLK1 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
4. | ALA5251366 | B | Inhibition of recombinant human CLK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
5. | ALA5251367 | B | Inhibition of recombinant human CLK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
6. | ALA5251368 | B | Inhibition of recombinant human CLK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
7. | ALA5251369 | B | Inhibition of recombinant human DYRK1A expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
8. | ALA5251370 | B | Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
9. | ALA5251371 | B | Inhibition of recombinant human DYRK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
10. | ALA5251372 | B | Inhibition of recombinant human DYRK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
11. | ALA5251373 | B | Inhibition of recombinant human DYRK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
12. | ALA5251374 | B | Inhibition of recombinant human GSK-3beta expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis | Homo sapiens | 56 | ALA5247649 | cell-based format | Scientific Literature | |
13. | ALA5251375 | B | Selectivity ratio of IC50 for recombinant human CLK1 expressed in Sf9 insect cells to IC50 for recombinant human DYRK1A expressed in Sf9 insect cells | Homo sapiens | 46 | ALA5247649 | cell-based format | Scientific Literature | |
14. | ALA5251376 | B | Selectivity ratio of IC50 for recombinant human DYRK1B expressed in Sf9 insect cells to IC50 for recombinant human DYRK1A expressed in Sf9 insect cells | Homo sapiens | 48 | ALA5247649 | cell-based format | Scientific Literature | |
15. | ALA5251377 | B | Selectivity ratio of IC50 for recombinant human GSK-3beta expressed in Sf9 insect cells to IC50 for recombinant human DYRK1A expressed in Sf9 insect cells | Homo sapiens | 48 | ALA5247649 | cell-based format | Scientific Literature | |
16. | ALA5251389 | B | Inhibition of DYRK1A in human SH-SY5Y cells assessed as reduction of Tau phosphorylation at Thr212 at 1 to 30 uM incubated for 6 hrs by SDS-PAGE based western blot assay | Homo sapiens | 4 | ALA5247649 | cell-based format | Scientific Literature | |
17. | ALA5251390 | T | Cytotoxicity against mouse HT-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay | Mus musculus | 56 | ALA5247649 | cell-based format | Scientific Literature | |
18. | ALA5251391 | B | Inhibition of DYRK1A in human SH-SY5Y cells assessed as decrease in total Tau protein expression level at 1 to 30 uM incubated for 6 hrs by SDS-PAGE based western blot assay | Homo sapiens | 7 | ALA5247649 | cell-based format | Scientific Literature |