# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5252889 | A | Substrate activity at human P-gp in vinblastine-resistant human KBV cells overexpressing human tau protein assessed as efflux ratio | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA5252919 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 0.5 uM and measured after 10 mins | Homo sapiens | 28 | microsome format | Scientific Literature | ||
3. | ALA5252920 | A | Metabolic stability in rat liver microsomes assessed as parent compound remaining at 0.5 uM and measured after 10 mins | Rattus norvegicus | 28 | microsome format | Scientific Literature | ||
4. | ALA5252921 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 0.5 uM and measured after 10 mins | Mus musculus | 28 | microsome format | Scientific Literature | ||
5. | ALA5252933 | B | Inhibition of GSK-3beta (unknown origin) assessed as decrease in tau phosphorylation by high content cell based assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
6. | ALA5252934 | B | Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assay | Homo sapiens | 33 | single protein format | Scientific Literature | ||
7. | ALA5252935 | B | Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assay | Homo sapiens | 34 | single protein format | Scientific Literature | ||
8. | ALA5252939 | A | Drug exposure in plasma of triple transgenic C57BL/6 mouse alzheimer disease model at 30 mg/kg,po and measured after 2 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA5252943 | F | Antialzheimer activity against triple transgenic C57BL/6 mouse alzheimer disease model assessed as reduction in tau phosphorylation at S396 at 30 mg/kg,po and measured upto 24 hrs by ELISA | Mus musculus | 5 | organism-based format | Scientific Literature |