# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5255823 | B | Inhibition of human proteasome trypsin-like activity using Boc-LRR-AMC as substrate measured for 30 mins in presence of MG132 by fluorescence based assay | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
2. | ALA5255824 | B | Inhibition of human proteasome chymotrypsin-like activity using suc-LLVY-AMC as fluorogenic substrate measured for 30 mins in presence of MG132 by fluorescence based assay | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
3. | ALA5255825 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability up to 200 uM measured for 9 hrs by WST-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA5255826 | B | Inhibition of proteasome caspase-like activity in human A549 cells at 25 uM using ZLLE-AMC as fluorogenic substrate preincubated for 15 mins followed by substrate addition and measured after 6 mins by fluorometer analysis | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
5. | ALA5255827 | B | Inhibition of proteasome caspase-like activity in human A549 cells assessed as LC3 lipidation at 25 to 100 uM measured for 12 hrs in presence of MG132 | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
6. | ALA5255828 | B | Inhibition of proteasome caspase-like activity in human A549 cells assessed as cleaved PARP level at 25 to 100 uM measured for 12 hrs in presence of MG132 | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
7. | ALA5255829 | B | Inhibition of proteasome caspase-like activity in human A549 cells assessed as increase in caspase-3 level at 25 to 100 uM measured for 12 hrs in presence of MG132 | Homo sapiens | 2 | subcellular format | Scientific Literature |