# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5230761 | Binding | Inhibition of CDK4 (unknown origin) assessed as inhibition constant using 32P-ATP as substrate preincubated for 20 mins followed by substrate addition and measured after 2 hrs by radioactive analysis | Homo sapiens | 1 | ALA5230096 | single protein format | Scientific Literature | |
2. | ALA5230762 | Binding | Inhibition of CDK6 (unknown origin) assessed as inhibition constant using 32P-ATP as substrate preincubated for 20 mins followed by substrate addition and measured after 2 hrs by radioactive analysis | Homo sapiens | 1 | ALA5230096 | single protein format | Scientific Literature | |
3. | ALA5230763 | Functional | Antiproliferative activity against human MV4-11 cells assessed as cell growth inhibition incubated for 72 hrs by resazurin assay | Homo sapiens | 1 | ALA5230096 | cell-based format | Scientific Literature | |
4. | ALA5230764 | Functional | Antiproliferative activity against human MDA-MB-453 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 1 | ALA5230096 | cell-based format | Scientific Literature | |
5. | ALA5230765 | ADME | AUC in Wistar rat at 20 mg/kg,po and measured upto 24 hrs by LC/MS/MS analysis | Rattus norvegicus | 1 | ALA5230096 | organism-based format | Scientific Literature | |
6. | ALA5230766 | ADME | AUC in Balb/c mouse at 10 mg/kg,po and measured upto 24 hrs by LC/MS/MS analysis | Mus musculus | 1 | ALA5230096 | organism-based format | Scientific Literature |