# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5243986 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as induction of mitotic arrest measured after 24 hrs by fluorescence high content cell imaging analysis | Homo sapiens | 32 | ALA5241130 | cell-based format | Scientific Literature | |
2. | ALA5243987 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as induction of polyploidy by fluorescence high content cell imaging analysis | Homo sapiens | 32 | ALA5241130 | cell-based format | Scientific Literature | |
3. | ALA5243990 | B | Disruption of mitotic localization of AURKB at the spindle mid-zone and equatorial cortex in human RPE-MYC cells expressing BCL2 at 40 nM measured after 6 hrs by immunofluorescence staining analysis | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
4. | ALA5243993 | B | Disruption of mitotic localization of AURKB in human RPE-MYC cells expressing BCL2 assessed as disruption of PLK1 localization at spindle mid-zone at 40 nM measured after 6 hrs by immunofluorescence staining analysis | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
5. | ALA5243995 | B | Disruption of mitotic localization of AURKB in human RPE-MYC cells expressing BCL2 assessed as disruption of MKLP1 localization at spindle mid-zone at 40 nM measured after 6 hrs by immunofluorescence staining analysis | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
6. | ALA5243996 | F | Cytotoxicity against human NCI-H23 cells assessed as cell growth inhibition incubated for 3 days by MTT assay | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
7. | ALA5243997 | F | Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 3 days by MTT assay | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
8. | ALA5243998 | F | Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 3 days by MTT assay | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
9. | ALA5243999 | F | Cytotoxicity against human SW480 cells assessed as cell growth inhibition incubated for 3 days by MTT assay | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
10. | ALA5244000 | F | Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 3 days by MTT assay | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
11. | ALA5244001 | F | Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 3 days by MTT assay | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
12. | ALA5244002 | F | Cytotoxicity against human NCI-N87 cells assessed as cell growth inhibition incubated for 3 days by MTT assay | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
13. | ALA5244051 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as induction of mitotic arrest by fluorescence high content cell imaging analysis | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
14. | ALA5244052 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as induction of polyploidy by fluorescence high content cell imaging analysis relative to control | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
15. | ALA5244053 | B | Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue at 8XMEC measured after 6 hrs by immunofluorescence staining analysis | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature | |
16. | ALA5244054 | B | Inhibition of AURKB in human RPE-MYC H2B-GFP cells assessed as inhibition of histone H3 phosphorylation at Ser10 residue at 8XMEC measured after 6 hrs by immunofluorescence staining analysis | Homo sapiens | 4 | ALA5241130 | cell-based format | Scientific Literature |