# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225197 | T | Cytotoxicity against mouse BV-2 cells assessed as cell viability at 5 uM incubated for 24 hrs by MTT assay relative to control | Mus musculus | 27 | ALA5223139 | cell-based format | Scientific Literature | |
2. | ALA5225198 | T | Cytotoxicity against mouse BV-2 cells assessed as cell viability at 10 uM incubated for 24 hrs by MTT assay relative to control | Mus musculus | 8 | ALA5223139 | cell-based format | Scientific Literature | |
3. | ALA5225199 | F | Inhibition of LPS-induced NO production in mouse BV-2 cells at 5 uM incubated for 24 hrs by Griess reagent based method relative to control | Mus musculus | 8 | ALA5223139 | cell-based format | Scientific Literature | |
4. | ALA5225200 | F | Inhibition of LPS-induced NO production in mouse BV-2 cells at 10 uM incubated for 24 hrs by Griess reagent based method relative to control | Mus musculus | 6 | ALA5223139 | cell-based format | Scientific Literature | |
5. | ALA5225201 | F | Inhibition of LPS-induced NO production in mouse BV-2 cells incubated for 24 hrs by Griess reagent based method | Mus musculus | 5 | ALA5223139 | cell-based format | Scientific Literature | |
6. | ALA5225202 | F | Antiinflammatory activity in LPS-induced mouse BV-2 cells assessed as reduction in iNOS mRNA expression pretreated for 1 hr followed by LPS stimulation and measured after 6 hrs by RT-PCR analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
7. | ALA5225203 | F | Antiinflammatory activity in LPS-induced mouse BV-2 cells assessed as reduction in COX-2 mRNA expression pretreated for 1 hr followed by LPS stimulation and measured after 6 hrs by RT-PCR analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
8. | ALA5225204 | F | Antiinflammatory activity in LPS-induced mouse BV-2 cells assessed as reduction in TNF-alpha mRNA expression pretreated for 1 hr followed by LPS stimulation and measured after 6 hrs by RT-PCR analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
9. | ALA5225205 | F | Antiinflammatory activity in LPS-induced mouse BV-2 cells assessed as reduction in IL-1beta mRNA expression pretreated for 1 hr followed by LPS stimulation and measured after 6 hrs by RT-PCR analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
10. | ALA5225206 | F | Antiinflammatory activity in LPS-induced mouse BV-2 cells assessed as reduction in IL-6 mRNA expression pretreated for 1 hr followed by LPS stimulation and measured after 6 hrs by RT-PCR analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
11. | ALA5225207 | F | Antiinflammatory activity in LPS-induced mouse BV-2 cells assessed as reduction in iNOS protein expression pretreated for 1 hr followed by LPS stimulation and measured after 18 hrs by Western blot analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
12. | ALA5225208 | F | Antiinflammatory activity in LPS-induced mouse BV-2 cells assessed as reduction in COX-2 protein expression pretreated for 1 hr followed by LPS stimulation and measured after 18 hrs by Western blot analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
13. | ALA5225209 | B | Inhibition of NF-kappaB activation in LPS-stimulated mouse BV-2 cells assessed as reduction in phosphorylated IkappaB-alpha level pretreated for 30 mins followed by LPS stimulation by Western blot analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
14. | ALA5225210 | B | Inhibition of NF-kappaB activation in LPS-stimulated mouse BV-2 cells assessed as reduction in phosphorylated p65 level pretreated for 30 mins followed by LPS stimulation by Western blot analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
15. | ALA5225211 | B | Inhibition of LPS-induced ERK phosphorylation in mouse BV-2 cells pretreated for 30 mins followed by LPS stimulation by Western blot analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
16. | ALA5225212 | B | Inhibition of LPS-induced p38 phosphorylation in mouse BV-2 cells at 5 to 20 uM pretreated for 30 mins followed by LPS stimulation by Western blot analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature | |
17. | ALA5225213 | B | Inhibition of LPS-induced JNK phosphorylation in mouse BV-2 cells at 5 to 20 uM pretreated for 30 mins followed by LPS stimulation by Western blot analysis | Mus musculus | 1 | ALA5223139 | cell-based format | Scientific Literature |