# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5239154 | B | Inhibition of C-terminal FLAG-His8-tagged full length human CTPS1 preincubated for 10 mins followed by substrate addition by ADP-Glo assay | Homo sapiens | 34 | ALA5236608 | single protein format | Scientific Literature | |
2. | ALA5239155 | F | Antiproliferative activity against human Jurkat E6.1 cells after 3 days by luminescence based CellTiter-glo assay | Homo sapiens | 33 | ALA5236608 | cell-based format | Scientific Literature | |
3. | ALA5239158 | A | Apparent permeability across apical to basolateral side in human Caco-2 cells at 10 uM measured after 2 hrs by LC-MS/MS analysis | Homo sapiens | 8 | ALA5236608 | cell-based format | Scientific Literature | |
4. | ALA5239159 | A | Efflux ratio of apparent permeability in human Caco-2 cells | Homo sapiens | 7 | ALA5236608 | cell-based format | Scientific Literature | |
5. | ALA5239160 | A | Stability in mouse hepatocytes assessed as clearance per 10^6 cells at 1 uM measured upto 60 mins by LC-MS/MS method | Mus musculus | 7 | ALA5236608 | cell-based format | Scientific Literature | |
6. | ALA5239164 | A | Cmax in BALB/C mouse at 10 mg/kg, po | Mus musculus | 1 | ALA5236608 | organism-based format | Scientific Literature | |
7. | ALA5239165 | A | AUC(0 to t) in BALB/C mouse at 10 mg/kg, po | Mus musculus | 1 | ALA5236608 | organism-based format | Scientific Literature | |
8. | ALA5239166 | A | Oral bioavailability in BALB/C mouse at 10 mg/kg | Mus musculus | 1 | ALA5236608 | organism-based format | Scientific Literature |