# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5250870 | B | Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate at 100 uM by fluorimetric analysis relative to control | Trypanosoma cruzi | 11 | single protein format | Scientific Literature | ||
2. | ALA5250871 | B | Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate at 100 uM preincubated for 10 mins followed by substrate addition by fluorimetric analysis relative to control | Trypanosoma cruzi | 9 | single protein format | Scientific Literature | ||
3. | ALA5250872 | B | Inhibition of TbrCatL using Z-FR-AMC as substrate at 100 uM by fluorimetric analysis relative to control | Trypanosoma brucei | 11 | assay format | Scientific Literature | ||
4. | ALA5250873 | B | Inhibition of TbrCatL using Z-FR-AMC as substrate at 100 uM preincubated for 10 mins followed by substrate addition by fluorimetric analysis relative to control | Trypanosoma brucei | 9 | assay format | Scientific Literature | ||
5. | ALA5250874 | B | Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysis | Trypanosoma cruzi | 9 | single protein format | Scientific Literature | ||
6. | ALA5250875 | B | Inhibition of TbrCatL using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysis | Trypanosoma brucei | 10 | assay format | Scientific Literature | ||
7. | ALA5250876 | B | Inhibition of Zika virus NS2B-NS3 protease using Bz-Nle-Lys-Lys-Arg-AMC as substrate at 0.78 uM preincubated for 10 mins followed by substrate addition relative to control | Zika virus | 2 | single protein format | Scientific Literature | ||
8. | ALA5250877 | F | Antiparasitic activity against Trypanosoma brucei incubated for 72 hrs by SYBR Green 1 dye based fluorescence assay | Trypanosoma brucei | 15 | organism-based format | Scientific Literature | ||
9. | ALA5250878 | F | Antiparasitic activity against Trypanosoma cruzi CA-I/72 incubated for 72 hrs by DAPI staining based microscopic analysis | Trypanosoma cruzi | 15 | organism-based format | Scientific Literature | ||
10. | ALA5250879 | T | Selectivity index, ratio of CC50 for mouse myoblasts cells to EC50 for Trypanosoma cruzi CA-I/72 | 4 | assay format | Scientific Literature | |||
11. | ALA5250880 | F | Potency index, ratio of pentamidine EC50 to test compound EC50 for antiparasitic activity against Trypanosoma cruzi CA-I/72 incubated for 72 hrs by DAPI staining based microscopic analysis | Trypanosoma cruzi | 1 | organism-based format | Scientific Literature | ||
12. | ALA5250881 | F | Potency index, ratio of benznidazole EC50 to test compound EC50 for antiparasitic activity against Trypanosoma cruzi CA-I/72 incubated for 72 hrs by DAPI staining based microscopic analysis | Trypanosoma cruzi | 1 | organism-based format | Scientific Literature | ||
13. | ALA5250882 | B | Inhibition of TbrCatL using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition in presence of 0% Triton by fluorimetric analysis | Trypanosoma brucei | 4 | assay format | Scientific Literature | ||
14. | ALA5250883 | B | Inhibition of TbrCatL using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition in presence of 0.01% Triton by fluorimetric analysis | Trypanosoma brucei | 4 | assay format | Scientific Literature | ||
15. | ALA5250884 | B | Inhibition of TbrCatL using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition in presence of 0.1% Triton by fluorimetric analysis | Trypanosoma brucei | 2 | assay format | Scientific Literature | ||
16. | ALA5250885 | B | Inhibition of TbrCatL using Z-FR-AMC as substrate preincubated for 10 mins in presence of BSA followed by substrate addition by fluorimetric analysis | Trypanosoma brucei | 4 | assay format | Scientific Literature | ||
17. | ALA5250886 | B | Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate at 0.25 to 1 uM incubated for 10 mins by fluorimetric analysis | Trypanosoma cruzi | 2 | single protein format | Scientific Literature |