| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5248761 | B | Inhibition of N-terminal his-tagged human recombinant LSD1 at 10 uM using 10-acetyl-3,7-dihydroxyphenoxazine as substrate measured for 30 mins by multiplate reader analysis relative to control | Homo sapiens | 44 | ALA5247583 | single protein format | Scientific Literature | |
| 2. | ALA5248762 | B | Inhibition of N-terminal his-tagged human recombinant LSD1 using 10-acetyl-3,7-dihydroxyphenoxazine as substrate measured for 30 mins by multiplate reader analysis | Homo sapiens | 43 | ALA5247583 | single protein format | Scientific Literature | |
| 3. | ALA5248763 | B | Inhibition of human recombinant LSD1 assessed as inhibition constant by HRP-coupled assay | Homo sapiens | 1 | ALA5247583 | single protein format | Scientific Literature | |
| 4. | ALA5248764 | B | Mixed inhibition of human recombinant LSD1 upto 50 uM in presence of H2O2 by HRP-coupled assay | Homo sapiens | 1 | ALA5247583 | single protein format | Scientific Literature | |
| 5. | ALA5248765 | B | Inhibition of recombinant MAO-A (unknown origin) using luciferin as substrate preincubated for 1 hr followed by substrate addition measured after 20 min by microplate reader analysis | Homo sapiens | 1 | ALA5247583 | single protein format | Scientific Literature | |
| 6. | ALA5248766 | B | Inhibition of recombinant MAO-B (unknown origin) using luciferin as substrate preincubated for 1 hr followed by substrate addition measured after 20 min by microplate reader analysis | Homo sapiens | 1 | ALA5247583 | single protein format | Scientific Literature | |
| 7. | ALA5248769 | B | Inhibition of SMOX (unknown origin) at 50 uM using spermine as substrate preincubated for 1 hr followed by substrate addition and measured after 20 mins by luminometer analysis relative to control | Homo sapiens | 1 | ALA5247583 | single protein format | Scientific Literature | |
| 8. | ALA5248770 | F | Upregulation of LSD1 expression level in human IMR-32 cells by DAPI staining based analysis | Homo sapiens | 1 | ALA5247583 | cell-based format | Scientific Literature | |
| 9. | ALA5248771 | B | Inhibition of LSD1 in human CHP-134 cells assessed as increase in H3K4me2 level at 0.111 uM measured for 72 hrs by DAPI staining based analysis relative to control | Homo sapiens | 1 | ALA5247583 | cell-based format | Scientific Literature | |
| 10. | ALA5248773 | B | Inhibition of LSD1 in human IMR-32 cells assessed as increase in H3K4me2 level at 0.333 uM measured for 72 hrs by DAPI staining based analysis relative to control | Homo sapiens | 2 | ALA5247583 | cell-based format | Scientific Literature | |
| 11. | ALA5248774 | F | Cytotoxicity against human CHP-134 cells assessed lethal concentration measured after 72 hrs by cell titer glo assay | Homo sapiens | 1 | ALA5247583 | cell-based format | Scientific Literature | |
| 12. | ALA5248775 | F | Cytotoxicity against human IMR-32 cells assessed lethal concentration measured after 72 hrs by cell titer glo assay | Homo sapiens | 1 | ALA5247583 | cell-based format | Scientific Literature | |
| 13. | ALA5248776 | F | Selectivity index, ratio of LC50 for human CHP-134 cells to LC50 for human IMR-32 cells | Homo sapiens | 1 | ALA5247583 | assay format | Scientific Literature | |
| 14. | ALA5248777 | F | Cytotoxicity against human CHP-134 cells measured after 24 hrs in presence of bortezomib by cell titer glo assay | Homo sapiens | 1 | ALA5247583 | cell-based format | Scientific Literature | |
| 15. | ALA5248779 | F | Cytotoxicity against human CHP-134 cells assessed as lethal concentration measured after 24 hrs in presence of bortezomib by cell titer glo assay | Homo sapiens | 2 | ALA5247583 | cell-based format | Scientific Literature | |
| 16. | ALA5248781 | F | Cytotoxicity against human IMR-32 cells assessed as lethal concentration measured after 24 hrs in presence of bortezomib by cell titer glo assay | Homo sapiens | 2 | ALA5247583 | cell-based format | Scientific Literature | |
| 17. | ALA5248782 | F | Potency index, ratio of bortezomib IC50 to compound IC50 for cytotoxicity against human IMR-32 cells assessed as lethal concentration measured after 24 hrs by cell titer glo assay | Homo sapiens | 2 | ALA5247583 | cell-based format | Scientific Literature | |
| 18. | ALA5248783 | F | Cytotoxicity against human IMR-32 cells assessed as combination index measured after 24 hrs by cell titer glo assay | Homo sapiens | 2 | ALA5247583 | cell-based format | Scientific Literature |
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