# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5250787 | Physicochemical | Thermodynamic aqueous solubility of compound at 25 degreeC measured after 24 hrs by HPLC analysis | 8 | ALA5247635 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA5250800 | Functional | Antileishmanial activity against GFP-expressing Leishmania infantum intracellular amastigotes infected in human THP-1 derived macrophage cells assessed as reduction in parasite viability measured for 72 hrs by resazurin/alamar blue fluorometric assay | Leishmania infantum | 14 | ALA5247635 | organism-based format | Scientific Literature | |
3. | ALA5250801 | Toxicity | Cytotoxicity against human HepG2 cells assessed as reduction in cell proliferation measured after 72 hrs by crystal violet staining based analysis | Homo sapiens | 14 | ALA5247635 | cell-based format | Scientific Literature | |
4. | ALA5250802 | Toxicity | Selectivity index, ratio of CC50 for human HepG2 cells to EC50 for GFP-expressing Leishmania infantum intracellular amastigotes infected in human THP-1 derived macrophage cells | 14 | ALA5247635 | cell-based format | Scientific Literature |