| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249475 | B | Inhibition of PI3Kgamma (unknown origin) at 10 uM preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assay relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 2. | ALA5249476 | B | Inhibition of PI3Kgamma (unknown origin) preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA5249477 | B | Inhibition of PI3Kalpha (unknown origin) preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA5249478 | B | Inhibition of PI3Kbeta (unknown origin) preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA5249479 | B | Inhibition of PI3Kdelta (unknown origin) preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA5249480 | B | Inhibition of PI3K/AKT signalling pathway in mouse RAW264.7 cells assessed as reduction in LPS-stimulated phosphorylation of AKT at Ser473 residue preincubated for 6 hrs followed by LPS stimulation for 6 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5249481 | B | Inhibition of PI3K/AKT signalling pathway in mouse RAW264.7 cells assessed as reduction in LPS-stimulated phosphorylation of AKT at Ser473 residue at 5 to 20 uM preincubated with compound followed by LPS stimulation for 6 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5249482 | B | Inhibition of PI3Kgamma in mouse RAW264 cells assessed as reduction in LPS-stimulated TNFalpha mRNA expression preincubated for 6 hrs followed by LPS addition and measured after 24 hrs by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5249483 | B | Inhibition of PI3Kgamma in mouse RAW264 cells assessed as reduction in LPS-stimulated IL-6 mRNA expression preincubated for 6 hrs followed by LPS addition and measured after 24 hrs by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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