# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5251392 | Functional | Ratio of MIC for Methicillin-resistant Staphylococcus aureus ATCC 43300 to MIC for wild type Staphylococcus aureus ATCC 29213 | Staphylococcus aureus | 2 | ALA5247650 | assay format | Scientific Literature | |
2. | ALA5251393 | Functional | Antibacterial activity against Enterococcus faecium ATCC 700221 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Enterococcus faecium | 15 | ALA5247650 | organism-based format | Scientific Literature | |
3. | ALA5251394 | Functional | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Enterococcus faecalis | 15 | ALA5247650 | organism-based format | Scientific Literature | |
4. | ALA5251395 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Staphylococcus aureus | 13 | ALA5247650 | organism-based format | Scientific Literature | |
5. | ALA5251396 | Binding | Inhibition of Escherichia coli DNA gyrase supercoiling | Escherichia coli | 10 | ALA5247650 | protein complex format | Scientific Literature | |
6. | ALA5251397 | Binding | Inhibition of Escherichia coli DNA topoisomerase 4 relaxation | Escherichia coli | 20 | ALA5247650 | assay format | Scientific Literature | |
7. | ALA5251398 | Functional | Antibacterial activity against Methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Staphylococcus aureus | 13 | ALA5247650 | organism-based format | Scientific Literature | |
8. | ALA5251399 | Functional | Antibacterial activity against Vancomycin-intermediate Staphylococcus aureus ATCC 700699 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Staphylococcus aureus | 15 | ALA5247650 | organism-based format | Scientific Literature | |
9. | ALA5251400 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Escherichia coli | 17 | ALA5247650 | organism-based format | Scientific Literature | |
10. | ALA5251401 | Functional | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Pseudomonas aeruginosa | 17 | ALA5247650 | organism-based format | Scientific Literature | |
11. | ALA5251402 | Functional | Antibacterial activity against Acinetobacter baumannii ATCC 17978 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Acinetobacter baumannii | 17 | ALA5247650 | organism-based format | Scientific Literature | |
12. | ALA5251403 | Functional | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Klebsiella pneumoniae | 17 | ALA5247650 | organism-based format | Scientific Literature | |
13. | ALA5251404 | Functional | Antibacterial activity against Enterobacter cloacae subsp. cloacae ATCC 13047 assessed as bacterial growth inhibition incubated for 18 hrs by microplate reader based analysis | Enterobacter cloacae | 15 | ALA5247650 | organism-based format | Scientific Literature | |
14. | ALA5251405 | Physicochemical | Thermodynamic solubility of compound in 100 mM PBS buffer at pH 7.4 incubated for 48 hrs under shaking condition by LC-MS/MS analysis | 10 | ALA5247650 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA5251406 | Physicochemical | Thermodynamic solubility of compound in 67 mM PBS buffer at pH 7.4 incubated for 24 hrs under shaking condition by LC-MS/MS analysis | 1 | ALA5247650 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA5251407 | ADME | Plasma protein binding in CD-1 mouse assessed as unbound fraction at 5 uM incubated for 4 hrs by equilibrium dialysis method | Mus musculus | 7 | ALA5247650 | cell-free format | Scientific Literature | |
17. | ALA5251408 | Physicochemical | Lipophilicity, logD of compound in octanol and potassium phosphate in pH 7.4 at 10 mM incubated for 48 hrs by LC-MS/MS analysis | 1 | ALA5247650 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA5251409 | Binding | Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysis | Staphylococcus aureus | 2 | ALA5247650 | protein complex format | Scientific Literature | |
19. | ALA5251410 | Binding | Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysis | Staphylococcus aureus | 2 | ALA5247650 | protein complex format | Scientific Literature | |
20. | ALA5251411 | Binding | Inhibition of Acinetobacter baumannii DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysis | Acinetobacter baumannii | 2 | ALA5247650 | assay format | Scientific Literature |