| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5260670 | B | Inhibition of recombinant PI5P4Kbeta (unknown origin) expressed in Escherichia coli BL21(DE3) at 100 uM by ADP-Glo reagent based assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA5260678 | B | Inhibition of recombinant PI5P4Kalpha (unknown origin) expressed in Escherichia coli BL21(DE3) by ADP-Glo reagent based assay | Homo sapiens | 43 | assay format | Scientific Literature | ||
| 3. | ALA5260679 | B | Inhibition of recombinant PI5P4Kgamma (unknown origin) expressed in Escherichia coli BL21(DE3) by ADP-Glo reagent based assay | Homo sapiens | 42 | assay format | Scientific Literature | ||
| 4. | ALA5260681 | B | Inhibition of PI5P4Kalpha in human HEK293 cells incubated for 60 mins by luminescence based analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA5260682 | A | Apparent permeability across apical to basolateral side in MDCK-MDR1 cells at 10 uM incubated for 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA5260683 | P | Aqueous solubility of compound in pH 7.4 | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA5260684 | A | Efflux ratio of apparent permeability across basolateral to apical membrane to apical to basolateral membrane in MDCK-MDR1 cells at 10 uM incubated for 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA5260685 | A | Metabolic stability in mouse liver microsomes assessed as half life at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 5 | microsome format | Scientific Literature | ||
| 9. | ALA5260686 | B | Inhibition of human PI5P4Kalpha assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA5260687 | B | Inhibition of human SPHK2 assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA5260688 | B | Inhibition of human ERK1 assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA5260689 | B | Inhibition of human JAK3 assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
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