#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5241960	B	Inverse agonist activity at human GAL4-fused RORgammat LBD (262 to 507 residues) transfected in HEK293T cell assessed as maxima inhibition measured after 24 hrs by dual luciferase assay relative to control	Homo sapiens	44	ALA5241082	cell-based format	Scientific Literature
2.	ALA5241961	B	Inverse agonist activity at human GAL4-fused FXR LBD transfected in 293T cell measured after 24 hrs by dual luciferase assay	Homo sapiens	6	ALA5241082	cell-based format	Scientific Literature
3.	ALA5241962	B	Inverse agonist activity at human GAL4-fused RORgamma LBD (262 to 507 residues) transfected in HEK293T cell measured after 24 hrs by dual luciferase assay	Homo sapiens	56	ALA5241082	cell-based format	Scientific Literature
4.	ALA5241963	B	Inverse agonist activity at human GAL4-fused LXRalpha LBD transfected in 293T cell measured after 24 hrs by dual luciferase assay	Homo sapiens	6	ALA5241082	cell-based format	Scientific Literature
5.	ALA5241964	B	Inverse agonist activity at human GAL4-fused RORbeta LBD transfected in 293T cell measured after 24 hrs by dual luciferase assay	Homo sapiens	6	ALA5241082	cell-based format	Scientific Literature
6.	ALA5241965	B	Inverse agonist activity at human GAL4-fused RORalpha LBD transfected in 293T cell measured after 24 hrs by dual luciferase assay	Homo sapiens	6	ALA5241082	cell-based format	Scientific Literature
7.	ALA5241966	B	Binding affinity to human RORgamma LBD (262 to 507 residues) expressed in Escherichia coli BL21(DE3) cells assessed as thermal stabilization by measuring change in melting temperature at 200 uM by thermal shift assay	Homo sapiens	56	ALA5241082	cell-based format	Scientific Literature
8.	ALA5241967	F	Antiproliferative activity against human LNCaP cells assessed as cell viability incubated for 96 hrs by Cell-Titer Glo assay	Homo sapiens	6	ALA5241082	cell-based format	Scientific Literature
9.	ALA5241968	F	Antiproliferative activity against human LNCaP C4-2B cells assessed as cell viability incubated for 96 hrs by Cell-Titer Glo assay	Homo sapiens	6	ALA5241082	cell-based format	Scientific Literature
10.	ALA5241969	F	Antiproliferative activity against human 22Rv1 cells assessed as cell viability incubated for 96 hrs by Cell-Titer Glo assay	Homo sapiens	6	ALA5241082	cell-based format	Scientific Literature
11.	ALA5241972	F	Reduction in PSA gene expression in human LNCaP cells at 10 uM incubated for 48 hrs by qRT-PCR analysis	Homo sapiens	1	ALA5241082	cell-based format	Scientific Literature
12.	ALA5241973	F	Reduction in KLK2 gene expression in human LNCaP cells at 10 uM incubated for 48 hrs by qRT-PCR analysis	Homo sapiens	1	ALA5241082	cell-based format	Scientific Literature
13.	ALA5241974	F	Reduction in TMPRSS2 gene expression in human LNCaP cells at 10 uM incubated for 48 hrs by qRT-PCR analysis	Homo sapiens	1	ALA5241082	cell-based format	Scientific Literature
14.	ALA5241978	F	Reduction in c-Myc gene expression in human LNCaP cells at 10 uM incubated for 48 hrs by qRT-PCR analysis	Homo sapiens	1	ALA5241082	cell-based format	Scientific Literature
15.	ALA5241982	A	Metabolic stability in human liver microsomes assessed as half life at 1 uM by HPLC-MS/MS analysis	Homo sapiens	5	ALA5241082	microsome format	Scientific Literature
16.	ALA5241983	A	Metabolic stability in rat liver microsomes assessed as half life at 1 uM by HPLC-MS/MS analysis	Rattus norvegicus	5	ALA5241082	microsome format	Scientific Literature
17.	ALA5241984	A	Cmax in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	4	ALA5241082	organism-based format	Scientific Literature
18.	ALA5241985	A	Tmax in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	4	ALA5241082	organism-based format	Scientific Literature
19.	ALA5241986	A	AUC (0 to t)in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	4	ALA5241082	organism-based format	Scientific Literature
20.	ALA5241987	A	AUC (0 to infinitive) in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	4	ALA5241082	organism-based format	Scientific Literature