# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225966 | A | Substrate activity at rat P-gp assessed as efflux ratio at 1 uM | Rattus norvegicus | 20 | assay format | Scientific Literature | ||
2. | ALA5225968 | B | Inhibition of GCS in human fibroblast | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
3. | ALA5225969 | A | Substrate activity at mouse BCRP assessed as efflux ratio at 1 uM | Mus musculus | 9 | single protein format | Scientific Literature | ||
4. | ALA5225970 | A | Substrate activity at mouse BCRP assessed as apparent permeability at 1 uM | Mus musculus | 9 | single protein format | Scientific Literature | ||
5. | ALA5225971 | B | Antagonist activity at human 5HT3A expressed in HEK293 cells incubated for 1 hr by FLIPR assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
6. | ALA5225972 | B | Selectivity ratio of IC50 for human 5HT3A to IC50 for GCS (unknown origin) | Homo sapiens | 9 | assay format | Scientific Literature | ||
7. | ALA5225973 | A | Clearance in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
8. | ALA5225974 | A | Intrinsic clearance in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
9. | ALA5225975 | A | Mean residence time in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
10. | ALA5225976 | A | Bioavailability in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | organism-based format | Scientific Literature |