# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5237550 | Binding | Inhibition of human CARM1 (140 to 480 residues) incubated for 15 mins measured after 60 min by AlphaLISA assay | Homo sapiens | 42 | ALA5236560 | single protein format | Scientific Literature | |
2. | ALA5237551 | ADME | Half life in ICR mouse at 10 mg/kg, po measured upto 24 hrs by UPLC analysis | Mus musculus | 1 | ALA5236560 | organism-based format | Scientific Literature | |
3. | ALA5237552 | ADME | Tmax in ICR mouse at 10 mg/kg, po measured upto 24 hrs by UPLC analysis | Mus musculus | 1 | ALA5236560 | organism-based format | Scientific Literature | |
4. | ALA5237553 | ADME | Cmax in ICR mouse at 10 mg/kg, po measured upto 24 hrs by UPLC analysis | Mus musculus | 1 | ALA5236560 | organism-based format | Scientific Literature | |
5. | ALA5237554 | ADME | AUClast in ICR mouse at 10 mg/kg, po measured upto 24 hrs by UPLC analysis | Mus musculus | 1 | ALA5236560 | organism-based format | Scientific Literature | |
6. | ALA5237555 | ADME | AUC(0 to infinity) in ICR mouse at 10 mg/kg, po measured upto 24 hrs by UPLC analysis | Mus musculus | 1 | ALA5236560 | organism-based format | Scientific Literature | |
7. | ALA5237556 | ADME | Metabolic stability in human liver microsomes assessed as parent compound remaining measured after 2 hrs | Homo sapiens | 1 | ALA5236560 | microsome format | Scientific Literature | |
8. | ALA5237557 | ADME | Metabolic stability in monkey liver microsomes assessed as parent compound remaining measured after 2 hrs | Macaca mulatta | 1 | ALA5236560 | microsome format | Scientific Literature | |
9. | ALA5237558 | ADME | Metabolic stability in dog liver microsomes assessed as parent compound remaining measured after 2 hrs | Canis lupus familiaris | 1 | ALA5236560 | microsome format | Scientific Literature | |
10. | ALA5237559 | ADME | Metabolic stability in rat liver microsomes assessed as parent compound remaining measured after 2 hrs | Rattus norvegicus | 1 | ALA5236560 | microsome format | Scientific Literature | |
11. | ALA5237560 | ADME | Metabolic stability in mouse liver microsomes assessed as parent compound remaining measured after 2 hrs | Mus musculus | 1 | ALA5236560 | microsome format | Scientific Literature | |
12. | ALA5237561 | Functional | Antiproliferative activity against human BT-549 cells assessed as cell growth inhibition incubated for 6 days by SRB assay | Homo sapiens | 18 | ALA5236560 | cell-based format | Scientific Literature | |
13. | ALA5237562 | Functional | Antiproliferative activity against human A-375 cells assessed as cell growth inhibition incubated for 6 days by SRB assay | Homo sapiens | 18 | ALA5236560 | cell-based format | Scientific Literature |