| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5256771 | B | Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP production preincubated for 15 mins followed by forskolin stimulation and measured after 5 hrs by luminescence based Steady glo assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA5256772 | B | Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP production by measuring maximum efficacy preincubated for 15 mins followed by forskolin stimulation and measured after 5 hrs by luminescence based Steady glo assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA5256773 | A | Stability in human liver microsomes assessed as intrinsic clearance preincubated for 60 mins followed by NADPH addition and measured upto 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 4. | ALA5256774 | A | Stability in rat liver microsomes assessed as intrinsic clearance preincubated for 60 mins followed by NADPH addition and measured upto 60 mins by LC-MS/MS analysis | Rattus norvegicus | 7 | microsome format | Scientific Literature |
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