# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5252414 | F | Cytoprotective activity in human ARPE-19 cells assessed as cell viability at 25 uM preincubated for 4 hrs followed by palmitate addition and measured after 24 hrs by cello-meter auto T4 bright field cell counter method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA5252415 | B | Agonist activity at human PPARalpha incubated for 22 to 24 hrs by luciferase assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
3. | ALA5252419 | F | Cytoprotective activity in human MIO-M1 cells assessed as decrease in VEGF secretion at 25 uM preincubated for 4 hrs followed by cobalt chloride addition measured by ELISA method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA5252420 | F | Cytoprotective activity in mouse 661W cells assessed as reduction in production of reactive oxygen species at 25 uM preincubated with compound for 4 hrs followed by palmitate addition and measured after 24 hrs by microplate reader analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
5. | ALA5252426 | B | Agonist activity at human PPARalpha at 0.5 uM incubated for 22 to 24 hrs by luciferase assay relative to GW7647 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
6. | ALA5252427 | B | Agonist activity at human PPARalpha at 5 uM incubated for 22 to 24 hrs by luciferase assay relative to GW7647 | Homo sapiens | 15 | single protein format | Scientific Literature | ||
7. | ALA5252429 | T | Cytotoxicity against human RPE cells measured upto 50 uM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA5252430 | B | Agonist activity at human PPARdelta at 0.013 to 100 uM incubated for 22 to 24 hrs by luciferase assay relative to GW0742 | Homo sapiens | 5 | single protein format | Scientific Literature | ||
9. | ALA5252431 | B | Agonist activity at human PPARgamma at 0.013 to 100 uM incubated for 22 to 24 hrs by luciferase assay relative to rosiglitazone | Homo sapiens | 5 | single protein format | Scientific Literature |