# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5243961 | B | Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 0.078 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
2. | ALA5243962 | B | Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 0.156 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
3. | ALA5243963 | B | Inhibition of AURKA in human RPE-MYC H2B-GFP cells assessed as inhibition of autophosphorylation of AURKA at Thr288 residue by measuring residual enzyme activity at 0.312 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-1%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
4. | ALA5243967 | B | Inhibition of AURKB in human RPE-MYC H2B-GFP cells assessed as inhibition of histone H3 phosphorylation at Ser10 residue by measuring residual enzyme activity at 0.078 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-9%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
5. | ALA5243968 | B | Inhibition of AURKB in human RPE-MYC H2B-GFP cells assessed as inhibition of histone H3 phosphorylation at Ser10 residue by measuring residual enzyme activity at 0.156 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-9%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
6. | ALA5243969 | B | Inhibition of AURKB in human RPE-MYC H2B-GFP cells assessed as inhibition of histone H3 phosphorylation at Ser10 residue by measuring residual enzyme activity at 0.312 uM measured after 6 hrs by immunofluorescence staining analysis (Rvb = 100 +/-9%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
7. | ALA5243973 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as proportion of polyploid cells in fully attached cell population at 0.078 uM measured after 48 hrs by fluorescence high content cell imaging analysis (Rvb <1%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
8. | ALA5243974 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as proportion of polyploid cells in fully attached cell population at 0.156 uM measured after 48 hrs by fluorescence high content cell imaging analysis (Rvb <1%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
9. | ALA5243975 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as proportion of polyploid cells in fully attached cell population at 0.312 uM measured after 48 hrs by fluorescence high content cell imaging analysis (Rvb <1%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
10. | ALA5243979 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as mitotic index at 0.078 uM measured after 6 hrs by fluorescence high content cell imaging analysis (Rvb = 4.7+/-0.4%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
11. | ALA5243980 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as mitotic index at 0.156 uM measured after 6 hrs by fluorescence high content cell imaging analysis (Rvb = 4.7+/-0.4%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature | |
12. | ALA5243981 | B | Disruption of mitotic localization of AURKB in human RPE-MYC H2B-GFP cells assessed as mitotic index at 0.312 uM measured after 6 hrs by fluorescence high content cell imaging analysis (Rvb = 4.7+/-0.4%) | Homo sapiens | 1 | ALA5241130 | cell-based format | Scientific Literature |