# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5256771 | Binding | Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP production preincubated for 15 mins followed by forskolin stimulation and measured after 5 hrs by luminescence based Steady glo assay | Homo sapiens | 8 | ALA5252666 | cell-based format | Scientific Literature | |
2. | ALA5256772 | Binding | Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP production by measuring maximum efficacy preincubated for 15 mins followed by forskolin stimulation and measured after 5 hrs by luminescence based Steady glo assay relative to control | Homo sapiens | 8 | ALA5252666 | cell-based format | Scientific Literature | |
3. | ALA5256773 | ADME | Stability in human liver microsomes assessed as intrinsic clearance preincubated for 60 mins followed by NADPH addition and measured upto 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | ALA5252666 | microsome format | Scientific Literature | |
4. | ALA5256774 | ADME | Stability in rat liver microsomes assessed as intrinsic clearance preincubated for 60 mins followed by NADPH addition and measured upto 60 mins by LC-MS/MS analysis | Rattus norvegicus | 7 | ALA5252666 | microsome format | Scientific Literature |