| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5237531 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 2. | ALA5237532 | F | Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 3. | ALA5237533 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 4. | ALA5237534 | F | Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 5. | ALA5237535 | B | Inhibition of recombinant rat TrxR expressed in Escherichia coli upto 100 nM using DTNB as substrate incubated for 30 mins in presence of NADPH by DTNB reduction assay | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 6. | ALA5237536 | B | Inhibition of glutathione reductase (unknown origin) incubated for 30 mins in presence of NADPH by spectrophotometric method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA5237537 | B | Inhibition of TrxR in human HL-60 cells at 2 uM incubated for 24 hrs by endpoint insulin reduction assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA5237538 | F | Cytotoxicity against human HeLa cells expressing TrxR assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5237539 | B | Inhibition of TrxR activity in human HL-60 cells incubated for 8 hrs by TRFS-green staining based microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5237540 | F | Induction of ROS production in human HL-60 cells assessed as increase in fluorescence intensity at 10 uM incubated for 2 hrs by DCFH-DA staining based fluorescent microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5237541 | F | Induction of ROS production in human HL-60 cells assessed as increase in red fluorescence incubated for 2 hrs by DHE staining based fluorescent microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5237542 | F | Induction of apoptosis in human HL-60 cells at 0.5 to 1 uM incubated for 24 hrs by Hoechst 33342 Staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5237543 | F | Induction of apoptosis in human HL-60 cells incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5237544 | F | Induction of apoptosis in human HL-60 cells assessed as activation of caspase-3 expression at 0.5 to 1 uM incubated for 12 hrs by colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5237545 | F | Induction of apoptosis in human HL-60 cells assessed as increase in cleaved caspase-3 level incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5237546 | F | Induction of apoptosis in human HL-60 cells assessed as decrease in procaspase-3 level incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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