# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5246536 | Functional | Cytotoxicity against parental mouse L5178Y cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Mus musculus | 39 | ALA5244266 | cell-based format | Scientific Literature | |
2. | ALA5246537 | Functional | Cytotoxicity against multi-drug resistant mouse L5178Y cells transfected with ABCB1 gene assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Mus musculus | 39 | ALA5244266 | cell-based format | Scientific Literature | |
3. | ALA5246538 | Binding | Modulation of P-glycoprotein mediated Rhodamine-123 efflux in multi-drug resistant mouse L5178Y cells tranfected with ABCB1 gene assessed as fluorescence activity ratio at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometric analysis (Rvb = 1.01 No_unit) | Mus musculus | 39 | ALA5244266 | cell-based format | Scientific Literature | |
4. | ALA5246539 | Binding | Modulation of P-glycoprotein mediated Rhodamine-123 efflux in multi-drug resistant mouse L5178Y cells tranfected with ABCB1 gene assessed as fluorescence activity ratio at 20 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometric analysis (Rvb = 1.01 No_unit) | Mus musculus | 40 | ALA5244266 | cell-based format | Scientific Literature |