| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5256457 | B | PROTAC activity at CRBN/H-PGDS in human KU812 cells assessed as induction of H-PGDS degradation by measuring decrease in H-PGDS protein expression incubated for 24 hrs by western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA5256458 | P | Solubility of the compound in PBS buffer at 100 uM at pH 7.4 by UPLC/MS/MS analysis | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA5256459 | P | Lipophilicity, logD of the compound by UPLC analysis | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA5256460 | A | Apparent permeability coefficient, Papp of the compound at pH 7.4 incubated for 4 hrs by UPLC/MS/MS analysis | 8 | assay format | Scientific Literature | |||
| 5. | ALA5256461 | A | Metabolic stability of the compound in human liver microsomes incubated for 10 mins in presence of NADPH by UPLC/MS/MS analysis | Homo sapiens | 8 | microsome format | Scientific Literature | ||
| 6. | ALA5256462 | A | Metabolic stability of the compound in human liver microsomes incubated for 60 mins in presence of NADPH by UPLC/MS/MS analysis | Homo sapiens | 8 | microsome format | Scientific Literature |
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