| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5251276 | B | Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate at 10 uM incubated for 30 mins by fluorescence based microplate reader assay | Homo sapiens | 48 | assay format | Scientific Literature | ||
| 2. | ALA5251277 | B | Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate incubated for 30 mins by fluorescence based microplate reader assay | Homo sapiens | 48 | assay format | Scientific Literature | ||
| 3. | ALA5251278 | B | Inhibition of recombinant LSD2 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA5251279 | B | Inhibition of recombinant human MAO-A at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA5251280 | B | Inhibition of recombinant human MAO-B at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA5251281 | B | Binding affinity to LSD1 (unknown origin) assessed as increase in thermostability incubated for 6 hrs by CESTA analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA5251282 | B | Inhibition of human LSD1 in human BGC-823 cells assessed as inhibition of H3K4me1 demethylation at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5251283 | B | Inhibition of human LSD1 in human BGC-823 cells assessed as inhibition of H3K4me2 demethylation at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5251284 | B | Inhibition of human LSD1 in human BGC-823 cells assessed as inhibition of H3K4me3 demethylation at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5251285 | B | Inhibition of human LSD1 in human LSD1 knockout BGC-823 cells assessed as effect on H3K4me1 methylation at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5251286 | B | Inhibition of human LSD1 in human LSD1 knockout BGC-823 cells assessed as effect on H3K4me2 methylation at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5251287 | B | Inhibition of human LSD1 in human LSD1 knockout BGC-823 cells assessed as effect on H3K4me3 methylation at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5251288 | F | Downregulation of PD-L1 expression in human BGC-823 cells at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5251289 | F | Downregulation of PD-L1 expression in mouse MFC cells at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5251290 | F | Downregulation of PD-L1 expression in human BGC-823 cell membrane at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 16. | ALA5251291 | F | Downregulation of PD-L1 expression in mouse MFC cell membrane at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Mus musculus | 1 | cell membrane format | Scientific Literature | ||
| 17. | ALA5251292 | F | Downregulation of PD-L1 expression in human LSD1 knockout BGC-823 cells at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5251293 | F | Downregulation of PD-L1 expression in mouse LSD1 knockout MFC cells at 5 to 20 uM incubated for 5 days by Western blot anlaysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5251294 | F | Downregulation of PD-L1 expression in human LSD1 knockout BGC-823 cells transfected with wild type LSD1 plasmid at 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5251295 | F | Downregulation of PD-L1 expression in human LSD1 knockout BGC-823 cells transfected with LSDI K661A mutant plasmid at 20 uM incubated for 5 days by Western blot anlaysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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