| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5228491 | Binding | Inhibition of human recombinant LSD1/CoREST using ART(mK)QTARKSTGGKAPRKQLAGGK-biotin as substrate incubated for 15 mins | Homo sapiens | 6 | ALA5226336 | protein complex format | Scientific Literature | |
| 2. | ALA5228492 | ADME | Substrate activity at p-glycoprotein (unknown origin) expressed in pig LLC-PK1 cells coexpressing MDR1 assessed as efflux ratio at apparent permeability across basolateral to apical side to apparent permeability across apical to basolateral side at 1 uM measured after 1 hr by LC-MS/MS analysis | Homo sapiens | 6 | ALA5226336 | cell-based format | Scientific Literature | |
| 3. | ALA5228495 | ADME | Drug metabolism in Sprague-Dawley rat brain assessed as N-(6-fluoro-4-methylpyridin-3-yl)acetamide level in cortex at 10 mg/kg, iv measured after 1 hr by HPLC-UV and LC/MS analysis | Rattus norvegicus | 1 | ALA5226336 | organism-based format | Scientific Literature | |
| 4. | ALA5228496 | ADME | Drug metabolism in Sprague-Dawley rat brain assessed as N-(6-fluoro-4-methylpyridin-3-yl)acetamide level in cortex at 10 mg/kg, iv measured after 4 hrs by HPLC-UV and LC/MS analysis | Rattus norvegicus | 1 | ALA5226336 | organism-based format | Scientific Literature |
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