# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5256856 | B | Binding affinity to recombinant human CTLA4 assessed as binding constant at 150 to 200 micromol/L measured for 600 sec bio-layer interferometry assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA5256857 | T | Cytotoxicity against mouse Lewis lung carcinoma cell line co-cultured with mouse CD8-positive T cell assessed as reduction in cell viability at 10 micromol/L by flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
3. | ALA5256858 | T | Cytotoxicity against mouse Lewis lung carcinoma cell line co-cultured with mouse CD8-positive T cell assessed as reduction in cell viability at 0.5 micromol/L by flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA5256859 | T | Cytotoxicity against mouse Lewis lung carcinoma cell line co-cultured with mouse CD8-positive T cell assessed as reduction in cell viability at 0.5 to 1 micromol/L measured up to 36 hrs by flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA5256860 | T | Cytotoxicity against mouse Lewis lung carcinoma cell line co-cultured with mouse CD8-positive T cell assessed as reduction in cell viability at 0.5 micromol/L measured up to 36 hrs by flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA5256861 | T | Cytotoxicity against mouse Lewis lung carcinoma cell line co-cultured with mouse CD8-positive T cell assessed as reduction in cell viability at 1 micromol/L measured up to 36 hrs by flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA5256862 | F | Antitumour activity against mouse Lewis lung carcinoma cell line allografted in C57BL/6 mouse assessed as reduction in tumor growth at 10 mg/kg, iv administered once daily for 2 days | Mus musculus | 1 | organism-based format | Scientific Literature |