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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5237905 B Antagonist activity at alpha2a-adrenoceptor (unknown origin) assessed as reduction in adrenaline-induced response by measuring equilibrium binding constant Homo sapiens 12 ALA5236573 single protein format Scientific Literature 2. ALA5237906 B Antagonist activity at alpha2c-adrenoceptor (unknown origin) assessed as reduction in adrenaline-induced response by measuring equilibrium binding constant Homo sapiens 12 ALA5236573 single protein format Scientific Literature 3. ALA5237907 B Selectivity index, ratio of Kb for antagonist activity at alpha2a-adrenoceptor (unknown origin) to Kb for antagonist activity at alpha2c-adrenoceptor (unknown origin) Homo sapiens 12 ALA5236573 assay format Scientific Literature 4. ALA5237908 A Metabolic stability in human hepatocytes assessed as clearance per 10^6 cells at 1 uM Homo sapiens 12 ALA5236573 cell-based format Scientific Literature 5. ALA5237909 A Metabolic stability in rat hepatocytes assessed as clearance per 10^6 cells at 1 uM Rattus norvegicus 12 ALA5236573 cell-based format Scientific Literature 6. ALA5237910 P Lipophilicity, logD of the compound 12 ALA5236573 small-molecule physicochemical format Scientific Literature 7. ALA5237911 P Solubility of the compound in pH 7.4 buffer 12 ALA5236573 small-molecule physicochemical format Scientific Literature 8. ALA5237912 A Permeability across apical to basolateral side in human Caco-2 cells Homo sapiens 12 ALA5236573 cell-based format Scientific Literature 9. ALA5237913 A Permeability across basolateral to apical side in human Caco-2 cells Homo sapiens 12 ALA5236573 cell-based format Scientific Literature 10. ALA5237914 A Efflux ratio of permeability across basolateral to apical side over apical to basolateral side in human Caco-2 cells Homo sapiens 12 ALA5236573 cell-based format Scientific Literature 11. ALA5237915 A Cmax in rat plasma at 1 mg/kg, po Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 12. ALA5237916 A Cmax in rat brain at 1 mg/kg, po Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 13. ALA5237917 A Tmax in rat plasma at 1 mg/kg, po Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 14. ALA5237918 A Tmax in rat brain at 1 mg/kg, po Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 15. ALA5237919 A AUC (0 to 6 hrs) in rat plasma at 1 mg/kg, po Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 16. ALA5237920 A AUC (0 to 6 hrs) in rat brain at 1 mg/kg, po Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 17. ALA5237921 A Unbound Cmax in rat plasma at 1 mg/kg, po by rapid equilibrium dialysis method Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 18. ALA5237922 A Unbound Cmax in rat brain at 1 mg/kg, po by rapid equilibrium dialysis method Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature 19. ALA5237923 A Unbound brain-to-plasma concentration ratio in rat at 1 mg/kg, po Rattus norvegicus 1 ALA5236573 organism-based format Scientific Literature 20. ALA5237924 A Unbound fraction in rat plasma at 1 mg/kg, po Rattus norvegicus 2 ALA5236573 organism-based format Scientific Literature