# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225563 | A | Half life in human liver microsomes | Homo sapiens | 3 | microsome format | Scientific Literature | ||
2. | ALA5225564 | F | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured at 24 hrs by MTT assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
3. | ALA5225565 | F | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured at 48 hrs by MTT assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
4. | ALA5225567 | T | Toxicity in nude mouse xenografted with human MCF7 cells assessed as side effects at 400 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA5225568 | P | Aqueous solubility of compound in PBS at pH 7.4 | 2 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA5225569 | A | Aqueous solubility of the compound in simulated gastric fluid | 2 | assay format | Scientific Literature | |||
7. | ALA5225570 | A | Aqueous solubility of the compound in simulated intestinal fluid | 2 | assay format | Scientific Literature | |||
8. | ALA5225571 | A | Permeability across apical to basolateral side in human Caco-2 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5225572 | A | Permeability across basolateral to apical side in human Caco-2 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA5225573 | P | Lipophilicity, logD of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA5225574 | A | Plasma protein binding in human relative to control | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
12. | ALA5225575 | A | Drug recovery in human plasma relative to control | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
13. | ALA5225576 | A | Inhibition of CYP2C8 in human liver microsomes at 10 uM relative to control | Homo sapiens | 2 | microsome format | Scientific Literature | ||
14. | ALA5225578 | A | Inhibition of CYP2C19 in human liver microsomes at 10 uM relative to control | Homo sapiens | 2 | microsome format | Scientific Literature | ||
15. | ALA5225579 | A | Inhibition of CYP3A in human liver microsomes at 10 uM relative to control | Homo sapiens | 2 | microsome format | Scientific Literature |