| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5237980 | F | Antimicrobial activity against Staphylococcus aureus ATCC25923 by two fold broth microdilution method | Staphylococcus aureus | 20 | ALA5236579 | organism-based format | Scientific Literature | |
| 2. | ALA5237981 | F | Antimicrobial activity against clinical isolates Staphylococcus aureus by two fold broth microdilution method | Staphylococcus aureus | 20 | ALA5236579 | organism-based format | Scientific Literature | |
| 3. | ALA5237982 | F | Antimicrobial activity against clinical isolates Bacillus cereus by two fold broth microdilution method | Bacillus cereus | 20 | ALA5236579 | organism-based format | Scientific Literature | |
| 4. | ALA5237983 | F | Antimicrobial activity against Escherichia coli ATCC27622 by two fold broth microdilution method | Escherichia coli | 20 | ALA5236579 | organism-based format | Scientific Literature | |
| 5. | ALA5237984 | F | Antimicrobial activity against Vibrio parahaemolyticus ATCC17802 by two fold broth microdilution method | Vibrio parahaemolyticus | 20 | ALA5236579 | organism-based format | Scientific Literature | |
| 6. | ALA5237985 | F | Bactericidal activity against Vibrio parahaemolyticus ATCC17802 assessed as killing rate at 0.5 X MIC by measuring time limit of detection by bacterial killing kinetic assay | Vibrio parahaemolyticus | 16 | ALA5236579 | organism-based format | Scientific Literature | |
| 7. | ALA5237989 | F | Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as massive cell collapse incubated at 5 times MIC and measured after 60 mins by scanning electron microscopy based analysis | Vibrio parahaemolyticus | 1 | ALA5236579 | organism-based format | Scientific Literature | |
| 8. | ALA5237990 | F | Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as surface fibrosis incubated at 5 times MIC and measured after 60 mins by scanning electron microscopy based analysis | Vibrio parahaemolyticus | 1 | ALA5236579 | organism-based format | Scientific Literature | |
| 9. | ALA5237991 | F | Induction of morphological changes in Vibrio parahaemolyticus ATCC17802 assessed as cellular inclusion leakage incubated at 5 times MIC and measured after 60 mins by scanning electron microscopy based analysis | Vibrio parahaemolyticus | 1 | ALA5236579 | organism-based format | Scientific Literature | |
| 10. | ALA5237997 | T | Cytotoxicity against human HaCaT cells incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA5236579 | cell-based format | Scientific Literature | |
| 11. | ALA5237998 | T | Cytotoxicity against mouse peritoneal macrophage cells incubated for 48 hrs by MTT assay | Mus musculus | 5 | ALA5236579 | cell-based format | Scientific Literature | |
| 12. | ALA5237999 | T | Hemolytic activity in human erythrocytes measured after 30 mins | Homo sapiens | 3 | ALA5236579 | cell-based format | Scientific Literature | |
| 13. | ALA5238000 | B | Induction of inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 at 5 times MIC measured upto 200 mins by propidium iodide penetration assay | Vibrio parahaemolyticus | 5 | ALA5236579 | cell membrane format | Scientific Literature | |
| 14. | ALA5238001 | B | Induction of inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as calcein leakage at 5 times MIC by calcein-AM leakage assay | Vibrio parahaemolyticus | 4 | ALA5236579 | cell membrane format | Scientific Literature | |
| 15. | ALA5238002 | B | Induction of inner membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as increase in PI fluorescence intensity at 5 times MIC by propidium iodide penetration assay | Vibrio parahaemolyticus | 10 | ALA5236579 | cell membrane format | Scientific Literature | |
| 16. | ALA5238005 | B | Induction of cytoplasmic membrane permeabilization in Vibrio parahaemolyticus ATCC1780 assessed as calcein transmembrane diffusion into interior of gaint unilamellar vesicles by measuring time to equilibrium between inside and outside of vesicles at 2 ug/mL by confocal microscopy based calcein-AM leakage assay | Vibrio parahaemolyticus | 3 | ALA5236579 | cell membrane format | Scientific Literature | |
| 17. | ALA5238006 | B | Binding affinity to Vibrio parahaemolyticus ATCC17802 cell membrane assessed as increase in fluorescence intensity measured after 30 mins by flow cytometry analysis (Rvb = 1.85%) | Vibrio parahaemolyticus | 3 | ALA5236579 | cell membrane format | Scientific Literature | |
| 18. | ALA5238007 | B | Binding affinity to Vibrio parahaemolyticus ATCC17802 cell membrane assessed as increase in fluorescence intensity measured after 120 mins by flow cytometry analysis (Rvb = 1.88%) | Vibrio parahaemolyticus | 3 | ALA5236579 | cell membrane format | Scientific Literature | |
| 19. | ALA5238008 | B | Induction of outer membrane permeabilization in Vibrio parahaemolyticus ATCC17802 assessed as increase fluorescence intensity at 0.5 to 2 times of MIC by NPN uptake assay | Vibrio parahaemolyticus | 3 | ALA5236579 | cell membrane format | Scientific Literature | |
| 20. | ALA5238009 | B | Induction of outer membrane permeabilization in Escherichia coli ATCC25722 assessed as increase fluorescence intensity at 0.5 to 2 times of MIC by NPN uptake assay | Escherichia coli | 3 | ALA5236579 | cell membrane format | Scientific Literature |
The page will load shortly, Thanks for your patience!