| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5227706 | B | Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by patch-clamp electrophysiology | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA5227707 | B | Inhibition of mouse ASIC1a expressed in genetically engineered-CHO-K1 cells at 10 uM preincubated for 10 mins at pH 7.4 followed by cell stimulation with proton injection at pH 6.5 by electro-chromic fluorescence voltage sensor-based assay relative to control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 3. | ALA5227708 | B | Inhibition of mouse ASIC2a expressed in genetically engineered-CHO-K1 cells at 10 uM preincubated for 10 mins at pH 7.4 followed by cell stimulation with proton injection at pH 6.5 by electro-chromic fluorescence voltage sensor-based assay relative to control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 4. | ALA5227715 | F | Neuroprotective activity in OGD/Rx-induced E16 Wistar rat Primary cortical neurons assessed as increase in cell viability at 1.9 uM incubated for 3 hrs during OGD followed by reoxygenation with compound re-addition measured after 21 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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