| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA630715 | A | First-order rate constant of the compound | 3 | assay format | Scientific Literature | |||
| 2. | ALA636556 | A | Maximum drug concentration (Vmax), relative to a control of 50 uM aminopterin included in each experiment. | 6 | assay format | Scientific Literature | |||
| 3. | ALA643134 | B | In vitro inhibitory activity against MOLT-4 T-cell leukemia cell AICAR transformylase | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA647426 | F | Compound was tested for cytotoxic activity in CCRF-CEM Human Leukemia cells by in vitro cytotoxicity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA655109 | F | Tested in vitro for cellular cytotoxicity against human T-cell derived lymphoblastic leukemia (CCRF-CEM) cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA669468 | B | In vitro inhibitory concentration against beef liver dihydrofolate reductase | Bos taurus | 4 | assay format | Scientific Literature | ||
| 7. | ALA879985 | B | Inhibition of dihydrofolate reductase (DHFR) in WIL2 cells | 7 | cell-based format | Scientific Literature | |||
| 8. | ALA677067 | B | Activity (apparent Km ) was evaluated in vitro by purified mouse liver folate polyglutamate synthetase (FPGS). | 6 | assay format | Scientific Literature | |||
| 9. | ALA678779 | B | Activity (relative Km ) was evaluated in vitro by purified mouse liver folate polyglutamate synthetase (FPGS). | 5 | assay format | Scientific Literature | |||
| 10. | ALA678781 | B | Activity (relative Vmax) was evaluated in vitro by purified mouse liver folate polyglutamate synthetase (FPGS). | 6 | assay format | Scientific Literature | |||
| 11. | ALA678880 | B | Km value of Hog folyl-poly-glutamate synthase in presence relative to aminopterin | Sus scrofa | 3 | single protein format | Scientific Literature | ||
| 12. | ALA678883 | B | Percent Vmax of Hog folyl-poly-glutamate synthase in presence relative to aminopterin | Sus scrofa | 3 | single protein format | Scientific Literature | ||
| 13. | ALA676939 | B | Compound was evaluated for the substrate activity for hog liver Folyl-polyglutamate synthase | Sus scrofa | 5 | assay format | Scientific Literature | ||
| 14. | ALA679517 | B | In vitro Folyl-poly-gamma-glutamyl synthetase (FPGS) affinity; No data | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 15. | ALA678806 | B | Inhibition of GAR transformylase in hog liver | Sus scrofa | 7 | tissue-based format | Scientific Literature | ||
| 16. | ALA678807 | B | In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactor | Sus scrofa | 13 | assay format | Scientific Literature | ||
| 17. | ALA873656 | B | Compound was evaluated for the inhibitory activity against GAR transformylase purified from mouse L1210 cells | 2 | cell-based format | Scientific Literature | |||
| 18. | ALA682627 | B | Tested in vitro for its inhibition of trifunctional glycinamide ribonucleotide formyltransferase (GARFT) isolated from murine L1210 leukemia cells | 3 | cell-based format | Scientific Literature | |||
| 19. | ALA885251 | F | Effective dose which is required to inhibit 50% of the cell growth of MCF-7 cells in culture. | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 20. | ALA712153 | F | In vitro inhibition of growth of MCF-7 human breast adenocarcinoma using 72 hours continuous exposure | Homo sapiens | 12 | cell-based format | Scientific Literature |
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