| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA666235 | B | The concentration required to inhibit dihydrofolate reductase in rat liver | 107 | tissue-based format | Scientific Literature | |||
| 2. | ALA3280527 | B | Inhibition of Escherichia coli dihydrofolate reductase | Escherichia coli | 11 | single protein format | Scientific Literature | ||
| 3. | ALA4271750 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 at 5 ug after 18 to 20 hrs by CLSI disk diffusion assay | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 4. | ALA4271751 | F | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 at 5 ug after 18 to 20 hrs by CLSI disk diffusion assay | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 5. | ALA4271752 | F | Antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus COL at 5 ug after 18 to 20 hrs by CLSI disk diffusion assay | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 6. | ALA4271753 | F | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 after 20 hrs by CLSI microdilution assay | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
| 7. | ALA4271754 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 after 20 hrs by CLSI microdilution assay | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
| 8. | ALA4271755 | F | Antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus COL after 20 hrs by CLSI microdilution assay | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
| 9. | ALA4271756 | F | Bactericidal activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 preincubated for 20 hrs followed by agar plating and measured after 18 to 20 hrs | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 10. | ALA4271757 | F | Bactericidal activity against methicillin-resistant Staphylococcus aureus USA300 preincubated for 20 hrs followed by agar plating and measured after 18 to 20 hrs | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 11. | ALA4271758 | F | Bactericidal activity against hospital-associated methicillin-resistant Staphylococcus aureus COL preincubated for 20 hrs followed by agar plating and measured after 18 to 20 hrs | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 12. | ALA4271759 | A | Cytotoxicity against human A549 cells after 24 to 48 hrs by fluorescence-based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4271760 | F | Potentiation of sulfamethoxazole-mediated antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 assessed as sulfamethoxazole MIC after 20 hrs by CLSI microdilution assay (Rvb = 100 microg/ml) | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA4271765 | F | Synergistic antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 in presence of sulfamethoxazole after 20 hrs by broth microdilution-based checkerboard titration assay | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 15. | ALA4271770 | F | Synergistic antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 assessed as fractional inhibitory concentration index in presence of sulfamethoxazole after 18 hrs by broth microdilution-based checkerboard titration assay | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 16. | ALA4271771 | F | Potentiation of sulfamethoxazole-mediated antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as sulfamethoxazole MIC after 20 hrs by CLSI microdilution assay (Rvb = 100 microg/ml) | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 17. | ALA4271776 | F | Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 in presence of sulfamethoxazole after 20 hrs by broth microdilution-based checkerboard titration assay | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 18. | ALA4271780 | F | Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as fractional inhibitory concentration index in presence of sulfamethoxazole after 18 hrs by broth microdilution-based checkerboard titration assay | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 19. | ALA4271781 | F | Potentiation of sulfamethoxazole-mediated antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus COL assessed as sulfamethoxazole MIC after 20 hrs by CLSI microdilution assay (Rvb = 200 microg/ml) | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 20. | ALA4271786 | F | Synergistic antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus COL in presence of sulfamethoxazole after 20 hrs by broth microdilution-based checkerboard titration assay | Staphylococcus aureus | 4 | organism-based format | Scientific Literature |
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