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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA809254 B Ability to inhibit thymidylate synthase derived from human leukemia K562 cells 9 ALA1123717 cell-based format Scientific Literature 2. ALA815671 B Evaluated for the inhibition of thymidylate synthase in intact L1210 cells 3 ALA1123906 cell-based format Scientific Literature 3. ALA815672 B Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cells 4 ALA1123906 cell-based format Scientific Literature 4. ALA1054500 F GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM Plasmodium falciparum 13,467 ALA1157539 organism-based format GSK Malaria Screening 5. ALA1054501 F GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM Plasmodium falciparum 13,467 ALA1157539 organism-based format GSK Malaria Screening 6. ALA1054502 F GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM Plasmodium falciparum 13,467 ALA1157539 organism-based format GSK Malaria Screening 7. ALA1054503 F GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. Plasmodium falciparum 13,467 ALA1157539 organism-based format GSK Malaria Screening 8. ALA1054504 F GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. Homo sapiens 13,467 ALA1157539 cell-based format GSK Malaria Screening 9. ALA1054505 F GSK_TCMDC: Inhibition Frequency Index (IFI). The number of non-kinase HTS assays where a compound showed > 50 % inhibition, expressed as a percentage of the number of such assays in which the compound was tested 13,467 ALA1157539 assay format GSK Malaria Screening 10. ALA3253412 B Inhibition of rat liver dihydrofolate reductase using dihydrofolate as substrate Rattus norvegicus 27 ALA3244206 assay format Scientific Literature 11. ALA3253413 B Inhibition of Streptococcus faecium dihydrofolate reductase using dihydrofolate as substrate Enterococcus faecium 27 ALA3244206 single protein format Scientific Literature