# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3744226 | F | Cytotoxicity against human MDA-MB-435 cells after 72 hrs by cell proliferation assay | Homo sapiens | 6 | ALA3739298 | cell-based format | Scientific Literature | |
2. | ALA3744227 | F | Cytotoxicity against human MDA-MB-231 cells after 72 hrs by cell proliferation assay | Homo sapiens | 6 | ALA3739298 | cell-based format | Scientific Literature | |
3. | ALA3744228 | F | Cytotoxicity against human OVCAR3 cells after 72 hrs by cell proliferation assay | Homo sapiens | 6 | ALA3739298 | cell-based format | Scientific Literature | |
4. | ALA3748575 | F | Cytotoxicity against multidrug resistant human MES-SA/Dx5 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 10 | ALA3745658 | cell-based format | Scientific Literature | |
5. | ALA3761145 | F | Cytotoxicity against human LNCAP cells after 72 hrs by AlamarBlue end point assay | Homo sapiens | 9 | ALA3758141 | cell-based format | Scientific Literature | |
6. | ALA3761146 | F | Cytotoxicity against human C4-2B cells after 72 hrs by AlamarBlue end point assay | Homo sapiens | 9 | ALA3758141 | cell-based format | Scientific Literature | |
7. | ALA3761148 | F | Cytotoxicity against human DuCaP cells after 72 hrs by AlamarBlue end point assay | Homo sapiens | 9 | ALA3758141 | cell-based format | Scientific Literature | |
8. | ALA3761149 | A | Cytotoxicity against human BPH1 cells after 72 hrs by AlamarBlue end point assay | Homo sapiens | 9 | ALA3758141 | cell-based format | Scientific Literature | |
9. | ALA3761150 | A | Cytotoxicity against human WPMY-1 cells after 72 hrs by AlamarBlue end point assay | Homo sapiens | 9 | ALA3758141 | cell-based format | Scientific Literature | |
10. | ALA3855791 | B | Inhibition of [3H]colchicine binding to microtubule associated proteins free porcine brain alpha/beta-tubulin assessed as remaining radiolabeled binding at 100 uM measured after 5 mins by centrifugal gel filtration method relative to control | Sus scrofa | 4 | ALA3853351 | assay format | Scientific Literature | |
11. | ALA3855792 | B | Inhibition of [3H]vinblastine binding to microtubule associated proteins free porcine brain alpha/beta-tubulin assessed as remaining radiolabeled binding at 100 uM measured after 5 mins by centrifugal gel filtration method relative to control | Sus scrofa | 4 | ALA3853351 | assay format | Scientific Literature | |
12. | ALA3857007 | F | Selectivity ratio of GI50 for human MES-SA/Dx5 cells to GI50 for human MES-SA cells | Homo sapiens | 2 | ALA3856201 | cell-based format | Scientific Literature | |
13. | ALA3861707 | F | Cytotoxicity against human K562 cells incubated for 72 hrs by CellTiter 96 aqueous one solution reagent based assay | Homo sapiens | 15 | ALA3860099 | cell-based format | Scientific Literature | |
14. | ALA3861708 | F | Cytotoxicity against doxorubicin-resistant human K562R cells incubated for 72 hrs by CellTiter 96 aqueous one solution reagent based assay | Homo sapiens | 15 | ALA3860099 | cell-based format | Scientific Literature | |
15. | ALA3861709 | F | Resistance index, ratio of IC50 for cytotoxicity against doxorubicin-resistant human K562R cells to IC50 for cytotoxicity against human K562 cells | Homo sapiens | 15 | ALA3860099 | cell-based format | Scientific Literature | |
16. | ALA3861710 | B | Inhibition of P-gp in doxorubicin-resistant human K562R cells assessed as rhodamine influx by measuring mean fluorescence intensity at 10 uM incubated for 20 mins by flow cytometry (Rvb = 1.8 No_unit) | Homo sapiens | 16 | ALA3860099 | cell-based format | Scientific Literature | |
17. | ALA3861711 | B | Inhibition of P-gp in doxorubicin-resistant human K562R cells assessed as rhodamine influx by measuring ratio of rhodamine mean fluorescence intensity in presence and absence of compound at 10 uM incubated for 20 mins by flow cytometry | Homo sapiens | 16 | ALA3860099 | cell-based format | Scientific Literature | |
18. | ALA3861712 | B | Inhibition of P-gp in doxorubicin-resistant human K562R cells assessed as rhodamine efflux by measuring mean fluorescence intensity at 10 uM incubated for 1 hr by flow cytometry (Rvb = 0.47 No_unit) | Homo sapiens | 16 | ALA3860099 | cell-based format | Scientific Literature | |
19. | ALA3861713 | B | Inhibition of P-gp in doxorubicin-resistant human K562R cells assessed as rhodamine efflux by measuring ratio of mean fluorescence intensity in presence and absence of compound at 10 uM incubated for 1 hr by flow cytometry | Homo sapiens | 16 | ALA3860099 | cell-based format | Scientific Literature | |
20. | ALA3861723 | T | Cytotoxicity against human MRC5 cells cells incubated for 72 hrs by CellTiter 96 aqueous one solution reagent based assay | Homo sapiens | 5 | ALA3860099 | cell-based format | Scientific Literature |