# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA629296 | Physicochemical | Compound was evaluated for pKa by titration of the compounds in 1:2 methyl alcohol and water. | 2 | ALA1123372 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA636434 | Physicochemical | Compound was evaluated for distribution coefficient | 3 | ALA1123372 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA635347 | Physicochemical | Partition coefficient (logP) | 3 | ALA1123372 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA642920 | Binding | Inhibition of [3H]WB-4101 binding to alpha adrenergic receptor from rat cerebral cortical membranes | 13 | ALA1121453 | cell membrane format | Scientific Literature | ||
5. | ALA650929 | Functional | Adrenergic agonist activity on guinea pig right atrial (Beta-1 adrenergic receptor) tissue | Cavia porcellus | 5 | ALA1130381 | tissue-based format | Scientific Literature | |
6. | ALA650940 | Binding | Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compound | Cavia porcellus | 5 | ALA1126148 | single protein format | Scientific Literature | |
7. | ALA650945 | Binding | Binding affinity against Beta-1 adrenergic receptor in guinea pig left ventricle | Cavia porcellus | 3 | ALA1126148 | single protein format | Scientific Literature | |
8. | ALA651559 | Functional | Compound was evaluated for its adenylyl cyclase activation at human Beta-1 adrenergic receptor | 1 | ALA1132774 | assay format | Scientific Literature | ||
9. | ALA651568 | Functional | Compound was evaluated for its inhibitory activity against human Beta-1 adrenergic receptor | 1 | ALA1132774 | assay format | Scientific Literature | ||
10. | ALA651832 | Functional | Intrinsic activity expressed as the percentage of maximal analogue response relative to the maximal response(100%) of isoproterenol against human beta-1-adrenoceptor using cAMP-RIA assay | 5 | ALA1132639 | assay format | Scientific Literature | ||
11. | ALA647362 | Functional | Drug concentration which produces cAMP response equal to 50% of its maximal response against human beta-1-adrenoceptor in chinese hamster ovary cells was determined | 3 | ALA1132639 | cell-based format | Scientific Literature | ||
12. | ALA647364 | Binding | Binding Affinity against human Beta-1 adrenergic receptor expressed in Chinese hamster ovary(CHO) cells was measured by using [125I]ICYP radioligand | 5 | ALA1132639 | cell-based format | Scientific Literature | ||
13. | ALA647365 | Binding | Binding affinity for human Beta-1 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol (ICYP).) PR = potency ratio relative to TMQ | Homo sapiens | 3 | ALA1129641 | cell-based format | Scientific Literature | |
14. | ALA651621 | Binding | Maximum response of drug relative to the response of 10e-5 isoproterenol after treatment with the compound | Cavia porcellus | 5 | ALA1126148 | single protein format | Scientific Literature | |
15. | ALA651623 | Functional | Potency ratio relative to TMQ for adrenergic activity on guinea pig tracheal (Beta-2 adrenergic receptor) tissue | Cavia porcellus | 9 | ALA1130381 | assay format | Scientific Literature | |
16. | ALA651625 | Functional | Potency ratio was measured as EC50 (trimetoquinol )/EC50 (drug) after treatment with the compound | Cavia porcellus | 4 | ALA1126148 | assay format | Scientific Literature | |
17. | ALA650093 | Functional | Adrenergic agonist activity on guinea pig tracheal (Beta-2 adrenergic receptor) tissue | Cavia porcellus | 6 | ALA1130381 | assay format | Scientific Literature | |
18. | ALA650094 | Binding | Beta-2 adrenergic receptor activity in guinea pig right atrium | Cavia porcellus | 3 | ALA1121684 | tissue-based format | Scientific Literature | |
19. | ALA651721 | Binding | Beta-2 adrenergic receptor activity in guinea pig tracheal smooth muscle | Cavia porcellus | 4 | ALA1121684 | single protein format | Scientific Literature | |
20. | ALA651041 | Binding | Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compound | Cavia porcellus | 5 | ALA1126148 | single protein format | Scientific Literature |