| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA629296 | P | Compound was evaluated for pKa by titration of the compounds in 1:2 methyl alcohol and water. | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA636434 | P | Compound was evaluated for distribution coefficient | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA635347 | P | Partition coefficient (logP) | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA642920 | B | Inhibition of [3H]WB-4101 binding to alpha adrenergic receptor from rat cerebral cortical membranes | 13 | cell membrane format | Scientific Literature | |||
| 5. | ALA650929 | F | Adrenergic agonist activity on guinea pig right atrial (Beta-1 adrenergic receptor) tissue | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 6. | ALA650940 | B | Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compound | Cavia porcellus | 5 | single protein format | Scientific Literature | ||
| 7. | ALA650945 | B | Binding affinity against Beta-1 adrenergic receptor in guinea pig left ventricle | Cavia porcellus | 3 | single protein format | Scientific Literature | ||
| 8. | ALA651559 | F | Compound was evaluated for its adenylyl cyclase activation at human Beta-1 adrenergic receptor | 1 | assay format | Scientific Literature | |||
| 9. | ALA651568 | F | Compound was evaluated for its inhibitory activity against human Beta-1 adrenergic receptor | 1 | assay format | Scientific Literature | |||
| 10. | ALA651832 | F | Intrinsic activity expressed as the percentage of maximal analogue response relative to the maximal response(100%) of isoproterenol against human beta-1-adrenoceptor using cAMP-RIA assay | 5 | assay format | Scientific Literature | |||
| 11. | ALA647362 | F | Drug concentration which produces cAMP response equal to 50% of its maximal response against human beta-1-adrenoceptor in chinese hamster ovary cells was determined | 3 | cell-based format | Scientific Literature | |||
| 12. | ALA647364 | B | Binding Affinity against human Beta-1 adrenergic receptor expressed in Chinese hamster ovary(CHO) cells was measured by using [125I]ICYP radioligand | 5 | cell-based format | Scientific Literature | |||
| 13. | ALA647365 | B | Binding affinity for human Beta-1 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol (ICYP).) PR = potency ratio relative to TMQ | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA651621 | B | Maximum response of drug relative to the response of 10e-5 isoproterenol after treatment with the compound | Cavia porcellus | 5 | single protein format | Scientific Literature | ||
| 15. | ALA651623 | F | Potency ratio relative to TMQ for adrenergic activity on guinea pig tracheal (Beta-2 adrenergic receptor) tissue | Cavia porcellus | 9 | assay format | Scientific Literature | ||
| 16. | ALA651625 | F | Potency ratio was measured as EC50 (trimetoquinol )/EC50 (drug) after treatment with the compound | Cavia porcellus | 4 | assay format | Scientific Literature | ||
| 17. | ALA650093 | F | Adrenergic agonist activity on guinea pig tracheal (Beta-2 adrenergic receptor) tissue | Cavia porcellus | 6 | assay format | Scientific Literature | ||
| 18. | ALA650094 | B | Beta-2 adrenergic receptor activity in guinea pig right atrium | Cavia porcellus | 3 | tissue-based format | Scientific Literature | ||
| 19. | ALA651721 | B | Beta-2 adrenergic receptor activity in guinea pig tracheal smooth muscle | Cavia porcellus | 4 | single protein format | Scientific Literature | ||
| 20. | ALA651041 | B | Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compound | Cavia porcellus | 5 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!