# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA638434 | A | Percent negation of rise in total serum cholesterol relative to control-fed 0.5% cholesterol for 7 days, At a dose of 0.3 mg/kg/day; percent reduction was not statistically significant | 1 | ALA1131497 | organism-based format | Scientific Literature | ||
2. | ALA638436 | A | Percent negation of rise in total serum cholesterol relative to control-fed 0.5% cholesterol for 7 days, At a dose of 1 mg/kg/day; percent reduction was not statistically significant | 1 | ALA1131497 | organism-based format | Scientific Literature | ||
3. | ALA877623 | A | Percent negation of rise in total serum cholesterol relative to control-fed 0.5% cholesterol for 7 days, At a dose of 3 mg/kg/day | 2 | ALA1131497 | organism-based format | Scientific Literature | ||
4. | ALA639120 | A | The pharmacokinetics property percent negation of rise in liver cholesterol esters relative to control-fed 0.5% cholesterol for 1 days, At a dose of 3 mg/kg/day | 1 | ALA1131497 | organism-based format | Scientific Literature | ||
5. | ALA639124 | A | The pharmacokinetics property percent negation of rise in liver cholesterol esters relative to control-fed 0.5% cholesterol for 7 days, At a dose of 0.3 mg/kg/day; percent reduction was not statistically significant | 1 | ALA1131497 | organism-based format | Scientific Literature | ||
6. | ALA639126 | A | The pharmacokinetics property percent negation of rise in liver cholesterol esters relative to control-fed 0.5% cholesterol for 7 days, At a dose of 3 mg/kg/day | 2 | ALA1131497 | organism-based format | Scientific Literature | ||
7. | ALA645925 | B | Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assay | 6 | ALA1127536 | assay format | Scientific Literature | ||
8. | ALA642850 | B | The concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity was measured at the dosage by using microsomal ACAT assay | 1 | ALA1127536 | assay format | Scientific Literature | ||
9. | ALA646534 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase in microsomal ACAT assay at 10 uM | Rattus norvegicus | 12 | ALA1127536 | assay format | Scientific Literature | |
10. | ALA643830 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) | 11 | ALA1121863 | single protein format | Scientific Literature | ||
11. | ALA646557 | B | In vitro for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver microsomes at 50 uM | Rattus norvegicus | 20 | ALA1129795 | tissue-based format | Scientific Literature | |
12. | ALA667933 | F | Compound was tested for the change in serum cholesterol (SC) levels in cholesterol fed dog | Canis lupus familiaris | 1 | ALA1121863 | organism-based format | Scientific Literature | |
13. | ALA692410 | F | Compound was tested for the change in liver cholesteryl ester (CE) levels by the inhibition of ACAT in hamster at 10 mg/kg p.o. | Cricetulus griseus | 1 | ALA1121863 | organism-based format | Scientific Literature | |
14. | ALA693582 | F | Compound was tested for the change in serum cholesterol (SC) levels by the inhibition of ACAT in hamster at 10 mg/kg p.o. | Cricetulus griseus | 1 | ALA1121863 | organism-based format | Scientific Literature | |
15. | ALA694520 | F | Compound was evaluated for the reduction of liver cholesterol ester levels in the cholesterol-fed Hamster model | Cricetulus griseus | 1 | ALA1159185 | organism-based format | Scientific Literature | |
16. | ALA694525 | F | Compound was tested for cholesterol reduction in liver in the cholesterol-fed hamster model after oral administration. | Cricetulus griseus | 6 | ALA1129144 | organism-based format | Scientific Literature | |
17. | ALA694529 | F | Compound was tested for the change in liver cholesterol (CE) levels in hamster | Cricetulus griseus | 1 | ALA1121863 | organism-based format | Scientific Literature | |
18. | ALA694328 | F | Dose required to inhibit cholesterol absorption in cholesterol fed hamster model | Cricetulus griseus | 8 | ALA1130740 | organism-based format | Scientific Literature | |
19. | ALA694329 | F | Dose required to inhibit cholesterol absorption in cholesterol fed hamster model | Cricetulus griseus | 5 | ALA1130741 | organism-based format | Scientific Literature | |
20. | ALA690239 | F | Effective dose evaluated in hamster cholesterol absorption assay | Cricetulus griseus | 3 | ALA1127536 | organism-based format | Scientific Literature |