# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA702022 | B | Ability to inhibit kynureninase was determined in a competitive inhibition assay. | 4 | single protein format | Scientific Literature | |||
2. | ALA702201 | B | Tested for inhibitory activity against Kynurenine 3-hydroxylase | 1 | single protein format | Scientific Literature | |||
3. | ALA702202 | B | Inhibition of rat kidney Kynurenine 3-hydroxylase. | 21 | single protein format | Scientific Literature | |||
4. | ALA702204 | B | Differences in inhibition of kynurenine-3-hydroxylase by m-NBA versus compound is determined | 4 | single protein format | Scientific Literature | |||
5. | ALA702205 | B | Ability to inhibit kynurenine-3-hydroxylase was determined in a competitive inhibition assay. | 4 | single protein format | Scientific Literature | |||
6. | ALA700046 | B | Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liver | 27 | assay format | Scientific Literature | |||
7. | ALA718176 | F | Sedative and anticonvulsant effects at dose 400 mg/kg, administered intraperitoneally; value expressed as clonic /tested =4/6 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA718177 | F | Sedative and anticonvulsant effects at dose 200 mg/kg, administered intraperitoneally; value expressed as clonic /tested =6/13 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA717509 | A | Sedative and anticonvulsant effects at dose 200 mg/kg, administered intraperitoneally; value expressed as death /tested =0/13 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA717510 | A | Sedative and anticonvulsant effects at dose 400 mg/kg, administered intraperitoneally; value expressed as death /tested =2/6 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA728836 | F | Sedative and anticonvulsant effects at dose 400 mg/kg, administered intraperitoneally; value expressed as tonic /tested =2/6 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA728837 | F | Sedative and anticonvulsant effects at dose 200 mg/kg, administered intraperitoneally; value expressed as tonic /tested =1/13 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA780655 | F | Effect on L-kynureninase (KYN) content in rat blood at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA780656 | F | Effect on L-kynureninase (KYN) content in rat brain at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
15. | ALA782436 | F | Effect on L-kynureninase (KYN) content in rat liver at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
16. | ALA779756 | F | Effect on kynurenic acid (KYNA) content in rat blood at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
17. | ALA779899 | F | Effect on kynurenic acid (KYNA) content in rat brain at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
18. | ALA779900 | F | Effect on kynurenic acid (KYNA) content in rat liver at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
19. | ALA3414281 | B | Inhibition of mouse KMO | Mus musculus | 1 | single protein format | Scientific Literature | ||
20. | ALA3630810 | B | Inhibition of human KMO | Homo sapiens | 4 | single protein format | Scientific Literature |