# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3630810 | Binding | Inhibition of human KMO | Homo sapiens | 4 | ALA3627665 | single protein format | Scientific Literature | |
2. | ALA702022 | Binding | Ability to inhibit kynureninase was determined in a competitive inhibition assay. | 4 | ALA1127625 | single protein format | Scientific Literature | ||
3. | ALA702201 | Binding | Tested for inhibitory activity against Kynurenine 3-hydroxylase | 1 | ALA1149923 | single protein format | Scientific Literature | ||
4. | ALA702202 | Binding | Inhibition of rat kidney Kynurenine 3-hydroxylase. | 21 | ALA1130431 | single protein format | Scientific Literature | ||
5. | ALA702204 | Binding | Differences in inhibition of kynurenine-3-hydroxylase by m-NBA versus compound is determined | 4 | ALA1127625 | single protein format | Scientific Literature | ||
6. | ALA702205 | Binding | Ability to inhibit kynurenine-3-hydroxylase was determined in a competitive inhibition assay. | 4 | ALA1127625 | single protein format | Scientific Literature | ||
7. | ALA700046 | Binding | Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liver | 27 | ALA1133168 | assay format | Scientific Literature | ||
8. | ALA718176 | Functional | Sedative and anticonvulsant effects at dose 400 mg/kg, administered intraperitoneally; value expressed as clonic /tested =4/6 | Mus musculus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
9. | ALA718177 | Functional | Sedative and anticonvulsant effects at dose 200 mg/kg, administered intraperitoneally; value expressed as clonic /tested =6/13 | Mus musculus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
10. | ALA717509 | ADME | Sedative and anticonvulsant effects at dose 200 mg/kg, administered intraperitoneally; value expressed as death /tested =0/13 | Mus musculus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
11. | ALA717510 | ADME | Sedative and anticonvulsant effects at dose 400 mg/kg, administered intraperitoneally; value expressed as death /tested =2/6 | Mus musculus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
12. | ALA3414281 | Binding | Inhibition of mouse KMO | Mus musculus | 1 | ALA3407478 | single protein format | Scientific Literature | |
13. | ALA780655 | Functional | Effect on L-kynureninase (KYN) content in rat blood at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
14. | ALA780656 | Functional | Effect on L-kynureninase (KYN) content in rat brain at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
15. | ALA782436 | Functional | Effect on L-kynureninase (KYN) content in rat liver at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
16. | ALA779756 | Functional | Effect on kynurenic acid (KYNA) content in rat blood at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
17. | ALA779899 | Functional | Effect on kynurenic acid (KYNA) content in rat brain at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
18. | ALA779900 | Functional | Effect on kynurenic acid (KYNA) content in rat liver at dose 400 mg/kg administered intraperitoneally | Rattus norvegicus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
19. | ALA728836 | Functional | Sedative and anticonvulsant effects at dose 400 mg/kg, administered intraperitoneally; value expressed as tonic /tested =2/6 | Mus musculus | 1 | ALA1127625 | organism-based format | Scientific Literature | |
20. | ALA728837 | Functional | Sedative and anticonvulsant effects at dose 200 mg/kg, administered intraperitoneally; value expressed as tonic /tested =1/13 | Mus musculus | 1 | ALA1127625 | organism-based format | Scientific Literature |