# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA839581 | ADME | Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6 | Homo sapiens | 60 | ALA1145288 | single protein format | Scientific Literature | |
2. | ALA829411 | ADME | Inhibitory concentration value against human cytochrome P-450 2A6 | Homo sapiens | 25 | ALA1145288 | single protein format | Scientific Literature | |
3. | ALA829412 | ADME | Inhibitory concentration value against human cytochrome P-450 2B6 | Homo sapiens | 25 | ALA1145288 | single protein format | Scientific Literature | |
4. | ALA829413 | ADME | Inhibitory concentration against human cytochrome P-450 2C9 | Homo sapiens | 25 | ALA1145288 | single protein format | Scientific Literature | |
5. | ALA829414 | ADME | Inhibitory concentration value against human cytochrome P-450 2D6 | Homo sapiens | 25 | ALA1145288 | single protein format | Scientific Literature | |
6. | ALA829415 | ADME | Inhibitory concentration value against human cytochrome P-450 2E1 | Homo sapiens | 25 | ALA1145288 | single protein format | Scientific Literature | |
7. | ALA829416 | ADME | Inhibitory concentration value against human cytochrome P-450 3A4 | Homo sapiens | 25 | ALA1145288 | single protein format | Scientific Literature | |
8. | ALA827104 | ADME | Inhibitory concentration value against human cytochrome P-450 2C19 | Homo sapiens | 25 | ALA1145288 | single protein format | Scientific Literature | |
9. | ALA832584 | ADME | Ratio of inhibition of human cytochrome P-450 2B6 to 2A6 was determined; Expressed as IC50(CYP2B6)/IC50(CYP2A6) | Homo sapiens | 25 | ALA1145288 | assay format | Scientific Literature | |
10. | ALA832585 | ADME | Ratio of inhibition of human cytochrome P-450 2C9 to 2A6 was determined; Expressed as IC50(CYP2C9)/IC50(CYP2A6) | Homo sapiens | 24 | ALA1145288 | assay format | Scientific Literature | |
11. | ALA832586 | ADME | Ratio of inhibition of human cytochrome P-450 2D6 to 2A6 was determined; Expressed as IC50(CYP2D6)/IC50(CYP2A6) | Homo sapiens | 25 | ALA1145288 | assay format | Scientific Literature | |
12. | ALA832587 | ADME | Ratio of inhibition of human cytochrome P-450 2E1 to 2A6 was determined; Expressed as IC50(CYP2E1)/IC50(CYP2A6) | Homo sapiens | 25 | ALA1145288 | assay format | Scientific Literature | |
13. | ALA832588 | ADME | Ratio of inhibition of human cytochrome P-450 3A4 to 2A6 was determined; Expressed as IC50(CYP3A4)/IC50(CYP2A6) | Homo sapiens | 25 | ALA1145288 | assay format | Scientific Literature | |
14. | ALA832592 | ADME | Ratio of inhibition of human cytochrome P-450 2C19 to 2A6 was determined; Expressed as IC50(CYP2C19)/IC50(CYP2A6) | Homo sapiens | 25 | ALA1145288 | assay format | Scientific Literature | |
15. | ALA4422401 | Binding | Inhibition of human CYP2A6 expressed in insect cell microsomes assessed as reduction in enzyme-mediated coumarin 7-hydroxylation | Homo sapiens | 111 | ALA4421730 | assay format | Patent Bioactivity Data | |
16. | ALA4422402 | Binding | Selectivity index, ratio of IC50 for inhibition of human CYP3A4 assessed as reduction in enzyme-mediated testosterone 6-hydroxylation to IC50 for inhibition of human CYP2A6 assessed as reduction in enzyme-mediated coumarin 7-hydroxylation | Homo sapiens | 106 | ALA4421730 | assay format | Patent Bioactivity Data | |
17. | ALA4422403 | ADME | Inhibition of CYP3A4 in human liver microsomes assessed as reduction in enzyme-mediated testosterone 6-hydroxylation in presence of NADPH-generating system, G6P and G6P dehydrogenase | Homo sapiens | 106 | ALA4421730 | microsome format | Patent Bioactivity Data | |
18. | ALA4422410 | ADME | Inhibition of human CYP2E1 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data | |
19. | ALA4422411 | ADME | Inhibition of human CYP2B6 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data | |
20. | ALA4422412 | ADME | Inhibition of human CYP2C9 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method | Homo sapiens | 43 | ALA4421730 | single protein format | Patent Bioactivity Data |