| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA800267 | F | Compound was tested for urinary glucose excretion (mg/24 h) at 100 mg/Kg dose of compound given perorally | Rattus norvegicus | 24 | tissue-based format | Scientific Literature | ||
| 2. | ALA838948 | A | Metabolic half-life as a measure of human liver microsomal stability was determined at 5 uM | Homo sapiens | 4 | tissue-based format | Scientific Literature | ||
| 3. | ALA840134 | A | In vivo ability to induce urinary glucose excretion in male Zucker Diabetic Fatty (ZDF) rats at 3 mg/kg i.v. dose | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA834934 | F | In vitro inhibition of Na-dependent [14C]AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 5. | ALA834935 | F | In vitro inhibition of Na-dependent [14C]AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 6. | ALA827615 | F | Ratio of Ki for sodium glucose co-transporter 1 and sodium glucose co-transporter 2 | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 7. | ALA863284 | B | Inhibitory activity towards human SGLT1 expressed in CHO-K1 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA863286 | B | Inhibitory activity towards human SGLT2 expressed in CHO-K1 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 9. | ALA869549 | B | Inhibitory activity against SGLT1 expressed in CHO-K1 cells | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 10. | ALA869552 | B | Inhibitory activity against SGLT2 expressed in CHO-K1 cells | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 11. | ALA868405 | F | Urinary glucose excretion in Zucker Diabetic Fatty rats at 2 mL/kg, iv 4 hrs post dose | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA867218 | A | AUC in Zucker Diabetic Fatty rats at 3 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA867724 | A | Half life in Zucker Diabetic Fatty rats at 3 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA867725 | A | Plasma clearance in Zucker Diabetic Fatty rats at 3 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA947997 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]AMG accumulation | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA947998 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]AMG accumulation | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA947999 | B | Selectivity for human SGLT2 over human SGLT1 | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 18. | ALA980893 | B | Selectivity for human SGLT2 over human SGLT1 expressed in Xenopus oocyte | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 19. | ALA977369 | B | Inhibition of human SGLT2 expressed in Xenopus oocyte assessed as [14C]alpha-methyl glucopyranoside uptake | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 20. | ALA961709 | B | Inhibition of human kidney SGLT2 assessed as renal glucose reabsorption | Homo sapiens | 8 | single protein format | Scientific Literature |
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