# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA682835 | B | Inhibition of [3H]estradiol binding to Estrogen receptor of MCF-7 cell lysate relative to tamoxifen | Homo sapiens | 3 | ALA1124143 | cell-based format | Scientific Literature | |
2. | ALA681896 | B | Inhibition of [3H]estradiol binding to calf uterine Estrogen receptor relative to tamoxifen | Bos taurus | 6 | ALA1124143 | protein format | Scientific Literature | |
3. | ALA712699 | F | Inhibition of MCF-7 human mammary tumor cell proliferation | Homo sapiens | 2 | ALA1124143 | cell-based format | Scientific Literature | |
4. | ALA712700 | F | Inhibition of MCF-7 human mammary tumor cell proliferation at 1*10e-6 M | Homo sapiens | 2 | ALA1124143 | cell-based format | Scientific Literature | |
5. | ALA709585 | F | Inhibition of MCF-7 human mammary tumor cell proliferation at 1*10e-7 M | Homo sapiens | 1 | ALA1124143 | cell-based format | Scientific Literature | |
6. | ALA706579 | F | Inhibition of MCF-7 human mammary tumor cell proliferation at 1*10e-8M | Homo sapiens | 2 | ALA1124143 | cell-based format | Scientific Literature | |
7. | ALA706581 | F | Inhibition of 1*10e-7 M estradiol induced proliferation of MCF-7 human mammary tumor cells at 1*10e-6 M | Homo sapiens | 1 | ALA1124143 | cell-based format | Scientific Literature | |
8. | ALA706582 | F | Inhibition of 1*10e-7 M estradiol induced proliferation of MCF-7 human mammary tumor cells at 1*10e-7 M | Homo sapiens | 1 | ALA1124143 | cell-based format | Scientific Literature | |
9. | ALA706583 | F | Inhibition of 1*10e-7 M estradiol induced proliferation of MCF-7 human mammary tumor cells at 1*10e-8M | Homo sapiens | 1 | ALA1124143 | cell-based format | Scientific Literature | |
10. | ALA706584 | F | Inhibition of 1*10e-8M estradiol induced proliferation of MCF-7 human mammary tumor cells | Homo sapiens | 1 | ALA1124143 | cell-based format | Scientific Literature | |
11. | ALA3295678 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in cell growth by measuring DNA level after 7 days by fluorescence analysis | Homo sapiens | 9 | ALA3286188 | cell-based format | Scientific Literature | |
12. | ALA3295679 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in cell growth by measuring DNA level at 10'-6 M after 7 days by fluorescence analysis | Homo sapiens | 6 | ALA3286188 | cell-based format | Scientific Literature | |
13. | ALA3295682 | B | Antagonist activity at ER in human MCF7:WS8 cells assessed as inhibition of estradiol-induced cell growth by measuring DNA level after 7 days treated at highesy drug concentration by fluorescence analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
14. | ALA3295684 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as cell growth by measuring DNA level at 0.56 X 10'-9 M after 7 days by fluorescence analysis | Homo sapiens | 1 | ALA3286188 | cell-based format | Scientific Literature | |
15. | ALA3295687 | B | Agonist activity at ER in rat GH3 cells assessed as increase in prolactin mRNA level at 10'-13 to 10'-6 M after 48 hrs by RT-PCR analysis relative to estradiol | Rattus norvegicus | 11 | ALA3286188 | cell-based format | Scientific Literature | |
16. | ALA3295689 | B | Antagonist activity at ER in rat GH3 cells assessed as inhibition of estradiol-induced prolactin gene expression at 10'-10 to 10'-6 M after 48 hrs by RT-PCR analysis | Rattus norvegicus | 9 | ALA3286188 | cell-based format | Scientific Literature | |
17. | ALA3295693 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in pS2 gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
18. | ALA3295694 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in GREB1 gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
19. | ALA3295695 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in PgR gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
20. | ALA3291522 | F | Effect on ER-alpha protein level in human MCF7:WS8 cells after 24 hrs by Western blot analysis relative to control | Homo sapiens | 13 | ALA3286188 | cell-based format | Scientific Literature |