# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA828503 | Binding | Inhibitory concentration against MMP-1 | 23 | ALA1139577 | single protein format | Scientific Literature | ||
2. | ALA828527 | Binding | Inhibitory concentration against MMP-13 | 23 | ALA1139577 | assay format | Scientific Literature | ||
3. | ALA827868 | Binding | Inhibitory concentration against rat TACE | Rattus norvegicus | 7 | ALA1139577 | single protein format | Scientific Literature | |
4. | ALA831580 | Functional | Inhibitory concentration against TNF-alpha release in LPS treated whole blood | Homo sapiens | 18 | ALA1139577 | tissue-based format | Scientific Literature | |
5. | ALA827846 | Binding | Inhibitory concentration against aggrecanase from porcine chondrocytes using [35S]-sulfate (5 mCi/ml) as radioligand and adding IL-1alpha (5 ng/ml) incubated for 10h | Sus scrofa | 19 | ALA1139577 | assay format | Scientific Literature | |
6. | ALA3880443 | Binding | Inhibition of trypsin-activated recombinant human collagenase 1 preincubated with protein followed by addition of DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMA)-NH2 as substrate measured after 20 mins by fluorescence analysis | Homo sapiens | 26 | ALA3880381 | single protein format | Patent Bioactivity Data | |
7. | ALA3880444 | Binding | Inhibition of APMA-activated recombinant human collagenase 3 preincubated with protein followed by addition of DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMA)-NH2 as substrate measured every 5 mins for 1 hr by fluorescence analysis | Homo sapiens | 26 | ALA3880381 | single protein format | Patent Bioactivity Data | |
8. | ALA3880445 | Binding | Inhibition of aggrecanase in primary porcine chondrocytes assessed as inhibition of 35S-proteoglycan release measured after 9 to 12 hrs by liquid scintillation counting method | Sus scrofa | 26 | ALA3880381 | cell-based format | Patent Bioactivity Data | |
9. | ALA3880446 | Binding | Inhibition of TACE in human mononuclear cells assessed as inhibition of LPS-induced TNF-alpha production measured after 4 hrs in presence of LPS by ELISA | Homo sapiens | 26 | ALA3880381 | cell-based format | Patent Bioactivity Data |