# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA837123 | F | Lethal concentration required to kill 50% Caki-1 cells of the human renal carcinoma with non-mutant wt p53 | Homo sapiens | 25 | ALA1138632 | cell-based format | Scientific Literature | |
2. | ALA837125 | F | Lethal concentration required to kill 50% C33A cells of the human cervical cells with a mutation at Cys 273 | Homo sapiens | 25 | ALA1138632 | cell-based format | Scientific Literature | |
3. | ALA837126 | F | Lethal concentration required to kill 50% Ramos RA1 cells of the human lymphocyte with a mutation at Asp 254 | Homo sapiens | 25 | ALA1138632 | cell-based format | Scientific Literature | |
4. | ALA825042 | F | Fold selectivity expressed as ratio of LC50 for Caki cells with non-mutant p53 to LC50 for C33A cells with a mutation at Cys 273 | Homo sapiens | 25 | ALA1138632 | cell-based format | Scientific Literature | |
5. | ALA825043 | F | Fold selectivity expressed as ratio of LC50 for Caki cells with non-mutant p53 to LC50 for Ramos RA1 cells with a mutation at Asp 254 | Homo sapiens | 25 | ALA1138632 | cell-based format | Scientific Literature | |
6. | ALA3382363 | B | Inhibition of C-terminal poly-His-tagged Escherichia coli MetAP expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition by fluorescence assay | Escherichia coli | 32 | ALA3351493 | assay format | Scientific Literature | |
7. | ALA3382364 | B | Inhibition of N-terminal poly-His-tagged Staphylococcus aureus COL MetAP expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition by fluorescence assay | Staphylococcus aureus subsp. aureus COL | 32 | ALA3351493 | assay format | Scientific Literature | |
8. | ALA3384241 | B | Inhibition of N-terminal poly-His-tagged human MetAP-1 expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition by fluorescence assay | Homo sapiens | 32 | ALA3351493 | assay format | Scientific Literature | |
9. | ALA3384242 | B | Inhibition of human MetAP-2 expressed in Sf9 cells incubated for 60 mins before MGMM substrate addition by fluorescence assay | Homo sapiens | 32 | ALA3351493 | cell-based format | Scientific Literature | |
10. | ALA3384243 | F | Antimicrobial activity against Escherichia coli BL21(DE3) assessed as inhibition of bacterial growth at 200 uM incubated at 37 degC for 7 hrs | Escherichia coli | 32 | ALA3351493 | assay format | Scientific Literature | |
11. | ALA3384246 | U | Glutathione reactivity assessed as second-order rate constant at 250 uM at pH 6.0 by HPLC-UV method | 9 | ALA3351493 | assay format | Scientific Literature | ||
12. | ALA3384247 | A | Cytotoxicity against human HaCaT cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
13. | ALA3384248 | A | Cytotoxicity against human Flow 2002 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
14. | ALA3384249 | F | Cytotoxicity against human A172 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
15. | ALA3384250 | F | Cytotoxicity against human Capan1 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
16. | ALA3384251 | F | Cytotoxicity against human CaSki cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
17. | ALA3384252 | F | Cytotoxicity against human SW707 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
18. | ALA3384253 | F | Cytotoxicity against human Calu6 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
19. | ALA3384254 | F | Cytotoxicity against human MeWo cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
20. | ALA3384255 | F | Cytotoxicity against human BT474 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature |