# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA828749 | B | Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coli | Rattus norvegicus | 9 | ALA1138773 | assay format | Scientific Literature | |
2. | ALA828092 | B | Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coli | Rattus norvegicus | 9 | ALA1138773 | assay format | Scientific Literature | |
3. | ALA829091 | B | Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand | Homo sapiens | 108 | ALA1138773 | assay format | Scientific Literature | |
4. | ALA829092 | B | Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coli | Mus musculus | 9 | ALA1138773 | assay format | Scientific Literature | |
5. | ALA829540 | B | Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand | Homo sapiens | 107 | ALA1138773 | assay format | Scientific Literature | |
6. | ALA829541 | B | Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coli | Mus musculus | 9 | ALA1138773 | assay format | Scientific Literature | |
7. | ALA835589 | B | Regulation of IGFBP-4 MRNA in SAOS-2 cells expressing human beta Estrogen receptor in terms of percent activity, relative to 10 nM 17-beta-estradiol | Homo sapiens | 17 | ALA1138773 | cell-based format | Scientific Literature | |
8. | ALA831723 | B | Selectivity fold for estrogen receptor beta over estrogen receptor alpha | Homo sapiens | 106 | ALA1138773 | protein format | Scientific Literature | |
9. | ALA837789 | F | Weight of rat uterine when treated with compound at 2 mg dose was determined | Rattus norvegicus | 4 | ALA1138773 | organism-based format | Scientific Literature | |
10. | ALA837794 | F | Weight of mouse uterine when treated with compound at 50 mg/kg dose was determined | Mus musculus | 10 | ALA1138773 | organism-based format | Scientific Literature | |
11. | ALA837797 | F | Weight of mouse uterine when treated with compound at 100 mg/kg dose was determined | Mus musculus | 1 | ALA1138773 | organism-based format | Scientific Literature | |
12. | ALA836282 | F | Weight of rat uterine when treated with combination of compound and Ethynyl estradiol was determined | Rattus norvegicus | 4 | ALA1138773 | organism-based format | Scientific Literature | |
13. | ALA837042 | F | Effect of combination of compound and testosterone propionate on androgen induced increase in ventral prostate weight; No change | Rattus norvegicus | 2 | ALA1138773 | tissue-based format | Scientific Literature | |
14. | ALA973102 | B | Binding affinity to ERbeta | 101 | ALA1157212 | single protein format | Scientific Literature | ||
15. | ALA1026551 | B | Selectivity ratio of RBA for ERbeta to RBA for ERalpha | 13 | ALA1152708 | assay format | Scientific Literature | ||
16. | ALA4263512 | B | Selectivity index, ratio of IC50 for full-length human ERalpha to IC50 for full length human ERbeta | Homo sapiens | 1 | ALA4261581 | assay format | Scientific Literature | |
17. | ALA4303805 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
18. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
19. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
20. | ALA4808149 | B | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 |