# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA834745 | Functional | Inhibitory concentration (toxicity at 10-20 mg/kg dose) exhibited against A549 cell line in mouse | Mus musculus | 4 | ALA1142765 | organism-based format | Scientific Literature | |
2. | ALA834746 | Functional | Inhibitory concentration (toxicity at 10-20 mg/kg dose) exhibited against MCF-7 cell line in mouse | Mus musculus | 4 | ALA1142765 | organism-based format | Scientific Literature | |
3. | ALA833295 | Functional | Inhibitory concentration (toxicity at 10-20 mg/kg dose) exhibited against SKOV3 cell line in mouse | Mus musculus | 4 | ALA1142765 | organism-based format | Scientific Literature | |
4. | ALA889450 | Functional | Increase in cellular tubulin polymer mass in HeLa cells assessed as minimum detectable effective concentration after 21 hrs | Homo sapiens | 12 | ALA1145389 | cell-based format | Scientific Literature | |
5. | ALA889451 | Functional | Growth inhibition of human 1A9 cells after 72 hrs | Homo sapiens | 12 | ALA1145389 | cell-based format | Scientific Literature | |
6. | ALA889452 | Functional | Growth inhibition of beta tubulin Phe270Val mutant expressing human 1A9/Ptx10 cells after 72 hrs | Homo sapiens | 12 | ALA1145389 | cell-based format | Scientific Literature | |
7. | ALA889453 | Functional | Growth inhibition of beta tubulin A364T mutant expressing human 1A9/Ptx22 cells after 72 hrs | Homo sapiens | 12 | ALA1145389 | cell-based format | Scientific Literature | |
8. | ALA889454 | Binding | Inhibition of bovine brain tubulin polymerization at 10 uM relative to paclitaxel | Bos taurus | 12 | ALA1145389 | assay format | Scientific Literature | |
9. | ALA889455 | Binding | Displacement of [3H]paclitaxel from bovine brain tubulin at 4 uM | Bos taurus | 11 | ALA1145389 | assay format | Scientific Literature |