# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA673365 | B | in vitro inhibitory activity against Dual specificity protein phosphatase 3 | 1 | ALA1132993 | single protein format | Scientific Literature | ||
2. | ALA696189 | B | in vitro inhibitory activity against He-PTP | 1 | ALA1132993 | assay format | Scientific Literature | ||
3. | ALA711894 | B | in vitro inhibitory activity against LAR | 1 | ALA1132993 | single protein format | Scientific Literature | ||
4. | ALA756510 | B | in vitro inhibitory activity against PTP-a | 1 | ALA1132993 | assay format | Scientific Literature | ||
5. | ALA768926 | B | In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B) | 114 | ALA1132993 | single protein format | Scientific Literature | ||
6. | ALA841818 | F | percentage decrease in plasma glucose in the ob/ob mouse model at 100 mg/kg/day administered per orally | Mus musculus | 1 | ALA1132993 | organism-based format | Scientific Literature | |
7. | ALA841819 | F | percentage decrease in plasma glucose in the ob/ob mouse model at 25 mg/kg/day administered per orally | Mus musculus | 1 | ALA1132993 | organism-based format | Scientific Literature | |
8. | ALA830840 | B | Concentration required for 50% inhibition of tyrosine phosphatase 1B | 59 | ALA1137823 | single protein format | Scientific Literature | ||
9. | ALA1118001 | B | Binding affinity to human recombinant PTP1B | Homo sapiens | 96 | ALA1155501 | single protein format | Scientific Literature | |
10. | ALA5246392 | B | Inhibition of human recombinant PTP1B (1 to 321 residues) expressed in Escherichia coli using TRDIYETDYYRK as peptide substrate incubated for 30 mins by by malachite green ammonium molybdate reagent assay | Homo sapiens | 4 | ALA5244260 | assay format | Scientific Literature | |
11. | ALA5246393 | B | Inhibition of LAR (unknown origin) | Homo sapiens | 1 | ALA5244260 | single protein format | Scientific Literature | |
12. | ALA5246394 | B | Inhibition of PTPalpha (unknown origin) | Homo sapiens | 1 | ALA5244260 | single protein format | Scientific Literature | |
13. | ALA5246395 | B | Inhibition of VHR (unknown origin) | Homo sapiens | 1 | ALA5244260 | single protein format | Scientific Literature | |
14. | ALA5246396 | B | Inhibition of HEPTP (unknown origin) | Homo sapiens | 1 | ALA5244260 | single protein format | Scientific Literature | |
15. | ALA5246397 | F | Anti-diabetic activity in ob/ob diabetic C57BL/6J mouse assessed as decrease in glucose level at 25 mg/kg,po dosed for 4 days | Mus musculus | 1 | ALA5244260 | organism-based format | Scientific Literature |