# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA828471 | B | Concentration required for inhibition of calpain | 4 | ALA1139620 | assay format | Scientific Literature | ||
2. | ALA3224718 | B | Inhibition of Ca2+-dependent activation of porcine calpain-1 using SucLY-AMC as substrate | Sus scrofa | 27 | ALA3217751 | single protein format | Scientific Literature | |
3. | ALA3224719 | B | Inhibition of Ca2+-dependent activation of porcine calpain-1 using H-K(FAM)-EVYGMMK(DABCYL)-OH as substrate by FRET assay | Sus scrofa | 27 | ALA3217751 | single protein format | Scientific Literature | |
4. | ALA3224721 | B | Inhibition of human erythrocytes mu-calpain using SLLVY-AMC as substrate after 60 mins | Homo sapiens | 2 | ALA3217751 | assay format | Scientific Literature | |
5. | ALA3224722 | B | Inhibition of calpain-2 (unknown origin) | Homo sapiens | 2 | ALA3217751 | single protein format | Scientific Literature | |
6. | ALA4263663 | B | Inhibition of full length porcine Calpain-1 complex using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assay | Sus scrofa | 11 | ALA4261589 | single protein format | Scientific Literature | |
7. | ALA4263664 | B | Inhibition of porcine Calpain-1 active site domain using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assay | Sus scrofa | 11 | ALA4261589 | single protein format | Scientific Literature | |
8. | ALA4263665 | B | Binding affinity to human Calpain-1 PEF(S) domain at 0.5 to 500 uM expressed in Escherichia coli BL21-CodonPlus (DE3) RP cells incubated for 5 mins by TNS displacement assay | Homo sapiens | 6 | ALA4261589 | cell-based format | Scientific Literature | |
9. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
10. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 |